STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
garR-22-hydroxy-3-oxopropionate reductase (Tartronate semialdehyde reductase). (289 aa)    
Predicted Functional Partners:
mmsA
Methylmalonate-semialdehyde dehydrogenase.
  
 
 0.913
puuC
gamma-Glu-gamma-aminobutyraldehyde dehydrogenase, NAD(P)H-dependent; Belongs to the aldehyde dehydrogenase family.
  
 
 0.912
betB
Betaine-aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.912
Rmet_1898
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.912
Rmet_3207
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.912
aptA
Beta-alanine-pyruvate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 
 0.901
Rmet_2585
Acetyl-CoA:acetoacetyl-CoA transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family.
  
  
  0.825
Rmet_0108
acyl-CoA dehydrogenase, short-chain specific.
  
 
 0.820
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
  
 
 0.809
Rmet_1061
acyl-CoA synthetase.
  
 
  0.807
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
Server load: low (10%) [HD]