STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pehRPolygalacturonase histidine response regulator. (560 aa)    
Predicted Functional Partners:
pehS
Polygalacturonase histidine kinase regulator.
 
 0.989
rpoN
RNA polymerase sigma 54 (sigma N) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.955
Rmet_3092
Conserved hypothetical protein.
  
    0.783
ampD
N-acetyl-anhydromuranmyl-L-alanine amidase.
       0.782
Rmet_3093
ABC-type transport system involved in cytochrome c biogenesis, permease component.
  
    0.752
pilL2
Type IV pilus protein histidine kinase/response regulator hybrid PilL.
 
 
 0.645
glnL
NtrB, signal transduction histidine kinase; nitrogen specific.
 
 0.590
evgS
Hybrid sensory histidine kinase in two-component regulatory system.
  
 
0.584
ffh
Signal Recognition Particle (SRP) component with 4.5S RNA (ffs); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex [...]
  
  
 0.549
Rmet_0591
Putative signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
  
 
 0.477
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.