STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mrcAPenicillin-binding protein 1A (PBP-1a): murein transglycosylase; murein transpeptidase. (792 aa)    
Predicted Functional Partners:
pbpC
Fused transglycosylase; transpeptidase; penicillin binding protein.
  
  
0.921
dac
D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
   
 
 0.909
mrcA1
Transpeptidase/transglycosylase (peniciline binding).
  
 
 
0.908
mrdA
Transpeptidase involved in peptidoglycan synthesis (penicillin-binding protein 2); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
 
 
 
 0.742
ftsI
Transpeptidase involved in septal peptidoglycan synthesis (penicillin-binding protein 3); Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
 
 
 0.711
murC
UDP-N-acetylmuramate:L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
  
 0.662
ftsW
Integral membrane protein involved in stabilizing FstZ ring during cell division; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily.
  
  
 0.661
yceG
Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
  
   
 0.652
ftsI1
Peptidoglycan glycosyltransferase (penicillin-binding domain).
 
 
 
 0.648
mrdB
Cell wall shape-determining protein MrdB; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
  
 0.638
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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