STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rpoLRNA polymerase sigma L factor (ECF:FecI-like); Belongs to the sigma-70 factor family. ECF subfamily. (177 aa)    
Predicted Functional Partners:
Rmet_3279
Putative transmembrane transcriptional regulator (anti-sigma factor).
 
 
 0.961
rpoP
RNA polymerase sigma P factor (ECF:RpoE-like); Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.886
rpoI
RNA polymerase sigma I (sigma 19) factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
  
 0.775
rpoE
RNA polymerase sigma 24 (sigma E) factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.775
Rmet_3281
Lipoprotein (secreted).
 
     0.770
rpoR
RNA polymerase sigma R factor (ECF); Belongs to the sigma-70 factor family. ECF subfamily.
      
 0.700
rseA
Anti-sigma factor, negative regulator of sigma24 activity.
  
 
 0.665
yedY
Exported heme-molybdoenzyme molybdopterin-containing subunit YedY; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospe [...]
  
  
 0.601
yedZ
Putative heme-molybdoenzyme heme-containing subunit YedZ; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reducta [...]
       0.598
Rmet_0596
Putative transmembrane transcriptional regulator (Anti-sigma factor).
  
 
 0.551
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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