STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ttuD2Hydroxypyruvate reductase. (443 aa)    
Predicted Functional Partners:
glxR
Tartronate semialdehyde reductase, NADH-dependent.
    
 0.954
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 
 0.944
tiaE
2-keto-D-gluconate reductase (glyoxalate reductase) (2-ketoaldonate reductase); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 0.942
ycdW
2-ketoacid reductase.
 
  
 0.918
eno-2
Enolase (2-phosphoglycerate dehydratase 2) (2-phospho- D-glycerate hydro-lyase 2); Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.911
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.910
gpmA
Phosphoglyceromutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
   
 
 0.906
Rmet_3207
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.906
garR
Tartronate semialdehyde reductase.
  
 
 0.905
ttuD
Hydroxypyruvate reductase.
  
 
 
0.904
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
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