STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cupAP-type ATPase CupA. (813 aa)    
Predicted Functional Partners:
sodC
Superoxide dismutase (Cu-Zn) 2 precursor; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
  
 0.960
cupR
DNA-binding transcriptional activator of copper-responsive regulon genes.
 
  
 0.942
cupC
Copper chaperone, heavy metal ion binding (modular protein).
 
 
 0.893
fieF
Cation Diffusion Factor, metal efflux system component; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
 
 
 0.719
rdxI
Heavy metal transporting P-type ATPase.
 
 
0.709
ctpA1
Metal transporter ATPase.
 
 
0.690
cadA
Lead/cadmium-transporting ATPase (cation efflux ATPase).
 
 
0.678
merP
Periplasmic mercury ion-binding protein; Involved in mercury resistance. Acts as a mercury scavenger that specifically binds to a mercuric ion in the periplasm and probably passes it to the cytoplasmic mercuric reductase MerA via the mercuric transport protein MerT.
 
 
 0.673
pldB
Lysophospholipase.
  
    0.650
dmeF
Co/Zn/Cd efflux system component.
  
  
 0.633
Your Current Organism:
Cupriavidus metallidurans
NCBI taxonomy Id: 266264
Other names: C. metallidurans CH34, Cupriavidus metallidurans CH34, Cupriavidus metallidurans str. CH34, Cupriavidus metallidurans strain CH34, Ralstonia metallidurans CH34, Wautersia metallidurans CH34
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.