| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rmet_2721 | hup | Rmet_2721 | Rmet_3538 | Putative glycosyltransferase, group 1 (probably involved in lipopolysaccharide biosynthesis). | Histone-like DNA-binding protein (HU); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.470 |
| Rmet_6601 | hup | Rmet_6601 | Rmet_3538 | Hypothetical protein. | Histone-like DNA-binding protein (HU); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.486 |
| acpP | hup | Rmet_2427 | Rmet_3538 | Acyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | Histone-like DNA-binding protein (HU); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.465 |
| acpP | ihfA | Rmet_2427 | Rmet_1166 | Acyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | Integration host factor, alpha subunit 1 (IHF-alpha 1); This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.824 |
| acpP | polA | Rmet_2427 | Rmet_2624 | Acyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | Fused DNA polymerase I 5'->3' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.644 |
| acpP | rplU | Rmet_2427 | Rmet_3106 | Acyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.976 |
| acpP | rpsO | Rmet_2427 | Rmet_0921 | Acyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 30S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.426 |
| dnaA | hup | Rmet_0001 | Rmet_3538 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Histone-like DNA-binding protein (HU); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.593 |
| dnaA | ihfA | Rmet_0001 | Rmet_1166 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Integration host factor, alpha subunit 1 (IHF-alpha 1); This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.490 |
| dnaA | polA | Rmet_0001 | Rmet_2624 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Fused DNA polymerase I 5'->3' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.418 |
| hslR | hup | Rmet_1002 | Rmet_3538 | Ribosome-associated heat shock protein. | Histone-like DNA-binding protein (HU); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.535 |
| hslR | ihfA | Rmet_1002 | Rmet_1166 | Ribosome-associated heat shock protein. | Integration host factor, alpha subunit 1 (IHF-alpha 1); This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.443 |
| hslR | rplU | Rmet_1002 | Rmet_3106 | Ribosome-associated heat shock protein. | 50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.829 |
| hup | Rmet_2721 | Rmet_3538 | Rmet_2721 | Histone-like DNA-binding protein (HU); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Putative glycosyltransferase, group 1 (probably involved in lipopolysaccharide biosynthesis). | 0.470 |
| hup | Rmet_6601 | Rmet_3538 | Rmet_6601 | Histone-like DNA-binding protein (HU); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Hypothetical protein. | 0.486 |
| hup | acpP | Rmet_3538 | Rmet_2427 | Histone-like DNA-binding protein (HU); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Acyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.465 |
| hup | dnaA | Rmet_3538 | Rmet_0001 | Histone-like DNA-binding protein (HU); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.593 |
| hup | hslR | Rmet_3538 | Rmet_1002 | Histone-like DNA-binding protein (HU); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Ribosome-associated heat shock protein. | 0.535 |
| hup | ihfA | Rmet_3538 | Rmet_1166 | Histone-like DNA-binding protein (HU); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Integration host factor, alpha subunit 1 (IHF-alpha 1); This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.626 |
| hup | polA | Rmet_3538 | Rmet_2624 | Histone-like DNA-binding protein (HU); Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Fused DNA polymerase I 5'->3' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.498 |