STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bxe_A0010Pterin-4-alpha-carbinolamine dehydratase; Phenylalanine degradation; Citation: J Neurogenet. 1999 Nov;13(3):157-80. (96 aa)    
Predicted Functional Partners:
Bxe_A0011
Phenylalanine degradation; Citation: J. Mol. Biol. 320 (3), 645-661 (2002).
 
 0.996
Bxe_A0286
4-hydroxyphenylpyruvate dioxygenase; Tyrosine degradation; Citation: Structure Fold. Des. 7 (8), 977-988(1999).
  
  
 0.790
Bxe_B2773
4-hydroxyphenylpyruvate dioxygenase; Tyrosine degradation; Citation: J. Bacteriol. 186 (15), 5062-5077 (2004).
  
  
 0.790
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
 
  
 0.629
hmgA-2
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
 
  
 0.629
Bxe_C0994
Homogentisate pathway; Citation: J. Bacteriol. 186 (15), 5062-5077 (2004).
 
  
 0.626
Bxe_A3154
Aminotransferase.
  
  
 0.613
Bxe_B1222
Aromatic amino acid aminotransferase apoenzyme.
  
  
 0.613
Bxe_C1025
Homogentisate pathway; J. Bacteriol. 186 (15), 5062-5077 (2004).
  
  
 0.577
Bxe_B0882
4-hydroxyphenylpyruvate dioxygenase.
  
  
 0.576
Your Current Organism:
Paraburkholderia xenovorans
NCBI taxonomy Id: 266265
Other names: Burkholderia cepacia LB400, Burkholderia fungorum LB400, Burkholderia sp. LB400, Burkholderia xenovorans LB400, P. xenovorans LB400, Paraburkholderia xenovorans LB400, Pseudomonas LB400, Pseudomonas sp. (strain LB400), Pseudomonas sp. LB400
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