STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bxe_A0429Putative chaperone. (416 aa)    
Predicted Functional Partners:
htpG
Putative chaperone protein; Molecular chaperone. Has ATPase activity.
  
 0.997
grpE
Putative heat shock protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of [...]
  
 0.992
dnaJ
Putative DnaJ chaperone protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...]
  
 0.967
rplP
LSU ribosomal protein L16P; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
   
 0.964
Bxe_B1015
Putative DnaJ-like protein.
  
 0.964
Bxe_B2345
Putative DnaJ chaperone protein.
  
 0.964
Bxe_A3108
Putative DnaJ-class molecular chaperone withC- terminal Zn finger domain, heat shock protein.
  
 0.958
Bxe_A0801
Putative ATP-dependent Clp protease ATP- binding subunit; Belongs to the ClpA/ClpB family.
  
 
 0.884
Bxe_A1887
Putative ATP-dependent Clp protease, ATP- binding subunit; Belongs to the ClpA/ClpB family.
  
 
 0.884
Bxe_A2096
Putative ClpA/B-type chaperone, ATPase subunit ClpB, heat shock protein; Citation: Watanabe YH, Takano M, Yoshida M.J BiolChem. 2005 Apr 4; [Epub ahead of print]. Shorter J, Lindquist S.Nat Struct Mol Biol. 2005 Jan;12(1):4-6; Belongs to the ClpA/ClpB family.
  
 
 0.884
Your Current Organism:
Paraburkholderia xenovorans
NCBI taxonomy Id: 266265
Other names: Burkholderia cepacia LB400, Burkholderia fungorum LB400, Burkholderia sp. LB400, Burkholderia xenovorans LB400, P. xenovorans LB400, Paraburkholderia xenovorans LB400, Pseudomonas LB400, Pseudomonas sp. (strain LB400), Pseudomonas sp. LB400
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