STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bxe_A2729hydroxymethylglutaryl-CoA lyase. (336 aa)    
Predicted Functional Partners:
Bxe_B0962
Putative enoyl coenzyme A hydratase-like protein; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.994
Bxe_A0469
Ketoathiolase (PaaJ); Phenylacetyl-CoA pathway; Citation: J. Bacteriol. 184 (22), 6301-6315 (2002).PNAS USA. 95 (11), 6419-6424 (1998). Environ Microbiol.2002 Dec;4(12):824-41; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.930
Bxe_A2342
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.930
Bxe_A2777
3-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.930
Bxe_A4036
Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.930
Bxe_A4255
Putative acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.930
Bxe_B0739
Thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.930
pcaF
Beta-ketoadipyl-CoA thiolase (pcaF); Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.930
sucC
succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.927
Bxe_B2809
Putative enoyl-CoA hydratase/isomerase.
 
 
  0.927
Your Current Organism:
Paraburkholderia xenovorans
NCBI taxonomy Id: 266265
Other names: Burkholderia cepacia LB400, Burkholderia fungorum LB400, Burkholderia sp. LB400, Burkholderia xenovorans LB400, P. xenovorans LB400, Paraburkholderia xenovorans LB400, Pseudomonas LB400, Pseudomonas sp. (strain LB400), Pseudomonas sp. LB400
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