potA-5 protein (Paraburkholderia xenovorans)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Score

potA-5

ABC spermidine/putrescine transporter, ATPase subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (357 aa)

Predicted Functional Partners:

Bxe_B1683

0.958

Bxe_B1684

0.955

Bxe_B0368

0.891

Bxe_B0749

0.891

Bxe_B2704

0.883

Bxe_B1872

0.882

Bxe_C1237

0.880

Bxe_B1682

0.878

Bxe_C1236

0.876

Bxe_B2542

0.875

Your Current Organism:

Paraburkholderia xenovorans

NCBI taxonomy Id: 266265
Other names: Burkholderia cepacia LB400, Burkholderia fungorum LB400, Burkholderia sp. LB400, Burkholderia xenovorans LB400, P. xenovorans LB400, Paraburkholderia xenovorans LB400, Pseudomonas LB400, Pseudomonas sp. (strain LB400), Pseudomonas sp. LB400

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bxe_B0368	potA-5	Bxe_B0368	Bxe_B1685	ABC peptide transporter, ATPase subunit; Belongs to the ABC transporter superfamily.	ABC spermidine/putrescine transporter, ATPase subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.	0.891
Bxe_B0749	Bxe_B1682	Bxe_B0749	Bxe_B1682	ABC polyamine/opine/phosphonate uptake family transporter, inner membrane subunit.	ABC spermidine/putrescine transporter, periplasmic ligand binding protein.	0.888
Bxe_B0749	Bxe_B1684	Bxe_B0749	Bxe_B1684	ABC polyamine/opine/phosphonate uptake family transporter, inner membrane subunit.	ABC spermidine/putrescine transporter, inner membrane subunit.	0.775
Bxe_B0749	Bxe_B1872	Bxe_B0749	Bxe_B1872	ABC polyamine/opine/phosphonate uptake family transporter, inner membrane subunit.	ABC transporter, inner membrane subunit.	0.910
Bxe_B0749	Bxe_B2542	Bxe_B0749	Bxe_B2542	ABC polyamine/opine/phosphonate uptake family transporter, inner membrane subunit.	ABC spermidine/putrescine transporter, inner membrane subunit.	0.925
Bxe_B0749	Bxe_C1236	Bxe_B0749	Bxe_C1236	ABC polyamine/opine/phosphonate uptake family transporter, inner membrane subunit.	ABC spermidine/putrescine transporter, inner membrane subunit.	0.782
Bxe_B0749	potA-5	Bxe_B0749	Bxe_B1685	ABC polyamine/opine/phosphonate uptake family transporter, inner membrane subunit.	ABC spermidine/putrescine transporter, ATPase subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.	0.891
Bxe_B1682	Bxe_B0749	Bxe_B1682	Bxe_B0749	ABC spermidine/putrescine transporter, periplasmic ligand binding protein.	ABC polyamine/opine/phosphonate uptake family transporter, inner membrane subunit.	0.888
Bxe_B1682	Bxe_B1683	Bxe_B1682	Bxe_B1683	ABC spermidine/putrescine transporter, periplasmic ligand binding protein.	ABC spermidine/putrescine transporter, inner membrane subunit.	0.977
Bxe_B1682	Bxe_B1684	Bxe_B1682	Bxe_B1684	ABC spermidine/putrescine transporter, periplasmic ligand binding protein.	ABC spermidine/putrescine transporter, inner membrane subunit.	0.976
Bxe_B1682	Bxe_B1872	Bxe_B1682	Bxe_B1872	ABC spermidine/putrescine transporter, periplasmic ligand binding protein.	ABC transporter, inner membrane subunit.	0.815
Bxe_B1682	Bxe_B2542	Bxe_B1682	Bxe_B2542	ABC spermidine/putrescine transporter, periplasmic ligand binding protein.	ABC spermidine/putrescine transporter, inner membrane subunit.	0.824
Bxe_B1682	Bxe_B2704	Bxe_B1682	Bxe_B2704	ABC spermidine/putrescine transporter, periplasmic ligand binding protein.	ABC spermidine/putrescine family transporter, inner membrane subunit.	0.876
Bxe_B1682	Bxe_C1236	Bxe_B1682	Bxe_C1236	ABC spermidine/putrescine transporter, periplasmic ligand binding protein.	ABC spermidine/putrescine transporter, inner membrane subunit.	0.850
Bxe_B1682	Bxe_C1237	Bxe_B1682	Bxe_C1237	ABC spermidine/putrescine transporter, periplasmic ligand binding protein.	ABC spermidine/putrescine transporter, inner membrane subunit.	0.893
Bxe_B1682	potA-5	Bxe_B1682	Bxe_B1685	ABC spermidine/putrescine transporter, periplasmic ligand binding protein.	ABC spermidine/putrescine transporter, ATPase subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.	0.878
Bxe_B1683	Bxe_B1682	Bxe_B1683	Bxe_B1682	ABC spermidine/putrescine transporter, inner membrane subunit.	ABC spermidine/putrescine transporter, periplasmic ligand binding protein.	0.977
Bxe_B1683	Bxe_B1684	Bxe_B1683	Bxe_B1684	ABC spermidine/putrescine transporter, inner membrane subunit.	ABC spermidine/putrescine transporter, inner membrane subunit.	0.942
Bxe_B1683	Bxe_B1872	Bxe_B1683	Bxe_B1872	ABC spermidine/putrescine transporter, inner membrane subunit.	ABC transporter, inner membrane subunit.	0.911
Bxe_B1683	Bxe_B2542	Bxe_B1683	Bxe_B2542	ABC spermidine/putrescine transporter, inner membrane subunit.	ABC spermidine/putrescine transporter, inner membrane subunit.	0.948

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

25

PPI enrichment p-value:

9.09e-08

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 128

1.69

4.18

7.28e-16

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019843

rRNA binding

11 of 44

2.15

7.64

8.20e-21

GO:0003735

Structural constituent of ribosome

11 of 57

2.04

6.81

5.26e-20

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 60

2.01

6.72

3.27e-20

GO:0015935

Small ribosomal subunit

3 of 8

2.33

2.45

1.91e-05

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:37185344

(2023) Independent origins and evolution of the secondary replicons of the class Gammaproteobacteria.

7 of 31

2.11

4.47

8.07e-11

PMID:28083017

(2016) Distribution of Hydrogenases in Cyanobacteria: A Phylum-Wide Genomic Survey.

6 of 20

2.23

4.29

9.18e-10

PMID:26096579

(2015) Neutral red-mediated microbial electrosynthesis by Escherichia coli, Klebsiella pneumoniae, and Zymomonas mobilis.

5 of 49

1.76

2.2

8.48e-06

PMID:37991636

(2023) De novo assembly and comparative genome analysis for polyhydroxyalkanoates-producing Bacillus sp. BNPI-92 strain.

3 of 36

1.67

0.93

0.0127

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:169

Ribosome

11 of 31

2.3

8.83

4.54e-22

CL:209

Small ribosomal subunit, and Ribosome

5 of 11

2.41

4.38

1.92e-09

CL:172

rRNA-binding

5 of 16

2.25

3.92

8.47e-09

CL:211

Small ribosomal subunit, and Ribosomal protein S13-like, H2TH

4 of 5

2.65

3.89

4.47e-08

CL:174

rRNA-binding

4 of 11

2.31

3.21

4.60e-07

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

reh03010

Ribosome

11 of 55

2.05

7.06

1.00e-20

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

10 of 52

2.04

6.21

1.65e-17

GOCC:0015935

Small ribosomal subunit

6 of 13

2.42

5.42

8.57e-12

GOCC:0044391

Ribosomal subunit

7 of 27

2.17

5.17

2.04e-12

GOCC:0022626

Cytosolic ribosome

5 of 21

2.13

3.68

1.42e-08

GOCC:0022627

Cytosolic small ribosomal subunit

4 of 9

2.4

3.53

1.25e-07

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0699

rRNA-binding

11 of 40

2.19

8.13

8.94e-22

KW-0689

Ribosomal protein

11 of 55

2.05

7.06

1.01e-20

KW-0820

tRNA-binding

2 of 17

1.82

0.84

0.0239

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