STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccmAABC heme exporter, ATPase subunit CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (228 aa)    
Predicted Functional Partners:
Bxe_C0371
ABC heme exporter, inner membrane subunit CcmB; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family.
 0.999
ccmC
ABC heme exporter, inner membrane subunit CcmC; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family.
 
 0.999
Bxe_A0348
Cytochrome c assembly protein.
  
 0.985
ccmE
Putative cytochrome c-type biogenesis protein CcmE; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family.
 
 
 0.954
Bxe_C0374
Cytochrome c-type biogenesis protein CcmF.
 
   
 0.924
Bxe_C0376
Putative cytochrome C biogenesis protein CcmH; Possible subunit of a heme lyase.
 
   
 0.920
Bxe_C0375
Periplasmic protein thiol-disulfide oxidoreductase DsbE.
 
   
 0.912
Bxe_C0377
Putative cytochrome c-type biogenesis protein.
 
   
 0.898
napC
Periplasmic nitrate reductase subunit NapC; Citation: Adv Microb Physiol 2001; 45:50-112.
 
  
 0.781
napB
Periplasmic nitrate reductase subunit NapB; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family.
 
    0.776
Your Current Organism:
Paraburkholderia xenovorans
NCBI taxonomy Id: 266265
Other names: Burkholderia cepacia LB400, Burkholderia fungorum LB400, Burkholderia sp. LB400, Burkholderia xenovorans LB400, P. xenovorans LB400, Paraburkholderia xenovorans LB400, Pseudomonas LB400, Pseudomonas sp. (strain LB400), Pseudomonas sp. LB400
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