STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Bxe_C1245Tryptophan 2-monooxygenase. (575 aa)    
Predicted Functional Partners:
Bxe_A0992
Putative histone deacetylase-family protein.
    
 0.981
Bxe_B1514
Putative histone deacetylase-family protein.
    
 0.981
Bxe_A0849
Conserved hypothetical protein; Weak similarity to helicase domain proteins.
    
 0.925
Bxe_A1202
Putative, plasmid-related, DNA/RNA helicase.
    
 0.925
Bxe_B1664
Putative helicase.
    
 0.925
Bxe_A4461
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
    0.784
Bxe_A2303
Putative phytoene synthase.
   
 
 0.727
Bxe_B0010
Putative squalene/phytoene synthase.
   
 
 0.727
Bxe_B0019
Putative squalene/phytoene synthase.
   
 
 0.727
Bxe_B0485
Farnesyl-diphosphate farnesyltransferase.
   
 
 0.727
Your Current Organism:
Paraburkholderia xenovorans
NCBI taxonomy Id: 266265
Other names: Burkholderia cepacia LB400, Burkholderia fungorum LB400, Burkholderia sp. LB400, Burkholderia xenovorans LB400, P. xenovorans LB400, Paraburkholderia xenovorans LB400, Pseudomonas LB400, Pseudomonas sp. (strain LB400), Pseudomonas sp. LB400
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