node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bxe_A0365 | Bxe_A3230 | Bxe_A0365 | Bxe_A3230 | Glutamate synthase (NADH) large subunit. | Acetolactate synthase, small subunit. | 0.634 |
Bxe_A0365 | Bxe_C1359 | Bxe_A0365 | Bxe_C1359 | Glutamate synthase (NADH) large subunit. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.893 |
Bxe_A0365 | ilvC | Bxe_A0365 | Bxe_A3229 | Glutamate synthase (NADH) large subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.878 |
Bxe_A0365 | ilvE | Bxe_A0365 | Bxe_A0686 | Glutamate synthase (NADH) large subunit. | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.474 |
Bxe_A0365 | ilvE-2 | Bxe_A0365 | Bxe_B0360 | Glutamate synthase (NADH) large subunit. | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.474 |
Bxe_A0365 | leuA | Bxe_A0365 | Bxe_A1435 | Glutamate synthase (NADH) large subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.403 |
Bxe_A0365 | leuA-2 | Bxe_A0365 | Bxe_A3225 | Glutamate synthase (NADH) large subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.403 |
Bxe_A3230 | Bxe_A0365 | Bxe_A3230 | Bxe_A0365 | Acetolactate synthase, small subunit. | Glutamate synthase (NADH) large subunit. | 0.634 |
Bxe_A3230 | Bxe_C1359 | Bxe_A3230 | Bxe_C1359 | Acetolactate synthase, small subunit. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.857 |
Bxe_A3230 | ilvC | Bxe_A3230 | Bxe_A3229 | Acetolactate synthase, small subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.999 |
Bxe_A3230 | ilvE | Bxe_A3230 | Bxe_A0686 | Acetolactate synthase, small subunit. | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.818 |
Bxe_A3230 | ilvE-2 | Bxe_A3230 | Bxe_B0360 | Acetolactate synthase, small subunit. | Branched chain amino acid aminotransferase apoenzyme; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.818 |
Bxe_A3230 | leuA | Bxe_A3230 | Bxe_A1435 | Acetolactate synthase, small subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.977 |
Bxe_A3230 | leuA-2 | Bxe_A3230 | Bxe_A3225 | Acetolactate synthase, small subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.978 |
Bxe_B1799 | Bxe_C1359 | Bxe_B1799 | Bxe_C1359 | Gluconolactonase. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.929 |
Bxe_B1799 | Bxe_C1362 | Bxe_B1799 | Bxe_C1362 | Gluconolactonase. | Xylono-1,4-lactonase. | 0.820 |
Bxe_C1358 | Bxe_C1359 | Bxe_C1358 | Bxe_C1359 | Conserved hypothetical protein. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.891 |
Bxe_C1359 | Bxe_A0365 | Bxe_C1359 | Bxe_A0365 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Glutamate synthase (NADH) large subunit. | 0.893 |
Bxe_C1359 | Bxe_A3230 | Bxe_C1359 | Bxe_A3230 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Acetolactate synthase, small subunit. | 0.857 |
Bxe_C1359 | Bxe_B1799 | Bxe_C1359 | Bxe_B1799 | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | Gluconolactonase. | 0.929 |