| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_0421 | Meso_0423 | Meso_0421 | Meso_0423 | KEGG: atu:Atu1660 hypothetical protein. | TIGRFAM: HAD-superfamily subfamily IIA hydrolase like protein HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase-like hydrolase; KEGG: bmb:BruAb2_0194 hydrolase, haloacid dehalogenase-like family. | 0.529 |
| Meso_0421 | Meso_0424 | Meso_0421 | Meso_0424 | KEGG: atu:Atu1660 hypothetical protein. | FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF cytidyltransferase-related domain; PFAM: Riboflavin kinase / FAD synthetase; KEGG: mlo:mlr8243 riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | 0.525 |
| Meso_0421 | hisG | Meso_0421 | Meso_0419 | KEGG: atu:Atu1660 hypothetical protein. | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity); Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.773 |
| Meso_0421 | hisS | Meso_0421 | Meso_0422 | KEGG: atu:Atu1660 hypothetical protein. | TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase, class II (G, H, P and S) Anticodon-binding; KEGG: bms:BRA0187 histidyl-tRNA synthetase. | 0.773 |
| Meso_0421 | hisZ | Meso_0421 | Meso_0420 | KEGG: atu:Atu1660 hypothetical protein. | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. | 0.773 |
| Meso_0423 | Meso_0421 | Meso_0423 | Meso_0421 | TIGRFAM: HAD-superfamily subfamily IIA hydrolase like protein HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase-like hydrolase; KEGG: bmb:BruAb2_0194 hydrolase, haloacid dehalogenase-like family. | KEGG: atu:Atu1660 hypothetical protein. | 0.529 |
| Meso_0423 | Meso_0424 | Meso_0423 | Meso_0424 | TIGRFAM: HAD-superfamily subfamily IIA hydrolase like protein HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase-like hydrolase; KEGG: bmb:BruAb2_0194 hydrolase, haloacid dehalogenase-like family. | FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF cytidyltransferase-related domain; PFAM: Riboflavin kinase / FAD synthetase; KEGG: mlo:mlr8243 riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | 0.835 |
| Meso_0423 | hisG | Meso_0423 | Meso_0419 | TIGRFAM: HAD-superfamily subfamily IIA hydrolase like protein HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase-like hydrolase; KEGG: bmb:BruAb2_0194 hydrolase, haloacid dehalogenase-like family. | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity); Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.603 |
| Meso_0423 | hisS | Meso_0423 | Meso_0422 | TIGRFAM: HAD-superfamily subfamily IIA hydrolase like protein HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase-like hydrolase; KEGG: bmb:BruAb2_0194 hydrolase, haloacid dehalogenase-like family. | TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase, class II (G, H, P and S) Anticodon-binding; KEGG: bms:BRA0187 histidyl-tRNA synthetase. | 0.782 |
| Meso_0423 | hisZ | Meso_0423 | Meso_0420 | TIGRFAM: HAD-superfamily subfamily IIA hydrolase like protein HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase-like hydrolase; KEGG: bmb:BruAb2_0194 hydrolase, haloacid dehalogenase-like family. | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. | 0.603 |
| Meso_0424 | Meso_0421 | Meso_0424 | Meso_0421 | FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF cytidyltransferase-related domain; PFAM: Riboflavin kinase / FAD synthetase; KEGG: mlo:mlr8243 riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | KEGG: atu:Atu1660 hypothetical protein. | 0.525 |
| Meso_0424 | Meso_0423 | Meso_0424 | Meso_0423 | FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF cytidyltransferase-related domain; PFAM: Riboflavin kinase / FAD synthetase; KEGG: mlo:mlr8243 riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | TIGRFAM: HAD-superfamily subfamily IIA hydrolase like protein HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase-like hydrolase; KEGG: bmb:BruAb2_0194 hydrolase, haloacid dehalogenase-like family. | 0.835 |
| Meso_0424 | hisG | Meso_0424 | Meso_0419 | FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF cytidyltransferase-related domain; PFAM: Riboflavin kinase / FAD synthetase; KEGG: mlo:mlr8243 riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity); Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | 0.525 |
| Meso_0424 | hisS | Meso_0424 | Meso_0422 | FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF cytidyltransferase-related domain; PFAM: Riboflavin kinase / FAD synthetase; KEGG: mlo:mlr8243 riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase, class II (G, H, P and S) Anticodon-binding; KEGG: bms:BRA0187 histidyl-tRNA synthetase. | 0.579 |
| Meso_0424 | hisZ | Meso_0424 | Meso_0420 | FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF cytidyltransferase-related domain; PFAM: Riboflavin kinase / FAD synthetase; KEGG: mlo:mlr8243 riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. | 0.525 |
| hisG | Meso_0421 | Meso_0419 | Meso_0421 | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity); Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | KEGG: atu:Atu1660 hypothetical protein. | 0.773 |
| hisG | Meso_0423 | Meso_0419 | Meso_0423 | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity); Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | TIGRFAM: HAD-superfamily subfamily IIA hydrolase like protein HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase-like hydrolase; KEGG: bmb:BruAb2_0194 hydrolase, haloacid dehalogenase-like family. | 0.603 |
| hisG | Meso_0424 | Meso_0419 | Meso_0424 | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity); Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF cytidyltransferase-related domain; PFAM: Riboflavin kinase / FAD synthetase; KEGG: mlo:mlr8243 riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | 0.525 |
| hisG | hisS | Meso_0419 | Meso_0422 | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity); Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase, class II (G, H, P and S) Anticodon-binding; KEGG: bms:BRA0187 histidyl-tRNA synthetase. | 0.982 |
| hisG | hisZ | Meso_0419 | Meso_0420 | ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity); Belongs to the ATP phosphoribosyltransferase family. Short subfamily. | ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. | 0.999 |
