Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Meso_0423TIGRFAM: HAD-superfamily subfamily IIA hydrolase like protein HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase-like hydrolase; KEGG: bmb:BruAb2_0194 hydrolase, haloacid dehalogenase-like family. (286 aa)    
Predicted Functional Partners:
Meso_0424
FMN adenylyltransferase; TIGRFAM: riboflavin biosynthesis protein RibF cytidyltransferase-related domain; PFAM: Riboflavin kinase / FAD synthetase; KEGG: mlo:mlr8243 riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family.
       0.835
hisS
TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase, class II (G, H, P and S) Anticodon-binding; KEGG: bms:BRA0187 histidyl-tRNA synthetase.
 
    0.782
Meso_0958
PFAM: metal-dependent phosphohydrolase, HD subdomain; KEGG: sme:SMc02559 hypothetical protein.
 
  
 0.714
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
    
   0.691
Meso_3923
Transcriptional regulator, XRE family; PFAM: helix-turn-helix motif; KEGG: atc:AGR_C_630 hypothetical protein.
  
     0.682
hisG
ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity); Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
 
     0.603
hisZ
ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
 
     0.603
Meso_0097
dCTP deaminase; PFAM: 2-deoxycytidine 5-triphosphate deaminase; KEGG: bmb:BruAb1_0332 dCTP deaminase.
 
    0.581
Meso_2145
Periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like histidine kinase, HAMP region histidine kinase A-like; KEGG: mlo:mlr2667 probable two-component sensor.
  
   0.577
Meso_0421
KEGG: atu:Atu1660 hypothetical protein.
       0.529
Your Current Organism:
Chelativorans sp. BNC1
NCBI taxonomy Id: 266779
Other names: C. sp. BNC1, Mesorhizobium sp. BNC1
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