| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_0056 | Meso_0564 | Meso_0056 | Meso_0564 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA1318 argininosuccinate lyase; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | 0.827 |
| Meso_0056 | Meso_1267 | Meso_0056 | Meso_1267 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: bmb:BruAb1_1204 isocitrate dehydrogenase, NADP-dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.934 |
| Meso_0056 | Meso_3329 | Meso_0056 | Meso_3329 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.530 |
| Meso_0056 | fumC | Meso_0056 | Meso_0355 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.966 |
| Meso_0056 | mdh | Meso_0056 | Meso_3395 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.992 |
| Meso_0056 | pckA | Meso_0056 | Meso_3502 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.638 |
| Meso_0564 | Meso_0056 | Meso_0564 | Meso_0056 | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA1318 argininosuccinate lyase; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.827 |
| Meso_0564 | Meso_1267 | Meso_0564 | Meso_1267 | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA1318 argininosuccinate lyase; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: bmb:BruAb1_1204 isocitrate dehydrogenase, NADP-dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.812 |
| Meso_0564 | Meso_1285 | Meso_0564 | Meso_1285 | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA1318 argininosuccinate lyase; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mlo:mll0079 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.917 |
| Meso_0564 | Meso_3329 | Meso_0564 | Meso_3329 | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA1318 argininosuccinate lyase; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.813 |
| Meso_0564 | arcA | Meso_0564 | Meso_2241 | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA1318 argininosuccinate lyase; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | TIGRFAM: arginine deiminase; PFAM: amidinotransferase; KEGG: hch:HCH_05490 arginine deiminase. | 0.907 |
| Meso_0564 | argD | Meso_0564 | Meso_0009 | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA1318 argininosuccinate lyase; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase, class I and II aminotransferase class-III; KEGG: mlo:mlr5646 acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.825 |
| Meso_0564 | argG | Meso_0564 | Meso_3344 | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA1318 argininosuccinate lyase; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | PFAM: argininosuccinate synthase; KEGG: mlo:mlr4366 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.992 |
| Meso_0564 | fumC | Meso_0564 | Meso_0355 | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA1318 argininosuccinate lyase; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.844 |
| Meso_0564 | mdh | Meso_0564 | Meso_3395 | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA1318 argininosuccinate lyase; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.823 |
| Meso_0564 | pckA | Meso_0564 | Meso_3502 | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA1318 argininosuccinate lyase; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.813 |
| Meso_1267 | Meso_0056 | Meso_1267 | Meso_0056 | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: bmb:BruAb1_1204 isocitrate dehydrogenase, NADP-dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.934 |
| Meso_1267 | Meso_0564 | Meso_1267 | Meso_0564 | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: bmb:BruAb1_1204 isocitrate dehydrogenase, NADP-dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: mac:MA1318 argininosuccinate lyase; Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. | 0.812 |
| Meso_1267 | Meso_1285 | Meso_1267 | Meso_1285 | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: bmb:BruAb1_1204 isocitrate dehydrogenase, NADP-dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; KEGG: mlo:mll0079 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.823 |
| Meso_1267 | fumC | Meso_1267 | Meso_0355 | TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; KEGG: bmb:BruAb1_1204 isocitrate dehydrogenase, NADP-dependent; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.627 |
