| node1 | node2 | node1 annotation | node2 annotation | score |
| Meso_0595 | Meso_0596 | Periplasmic sensor diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: conserved hypothetical protein EAL CHASE4; KEGG: sme:SMa0137 putative kinase/esterase. | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR response regulator receiver sigma-70 region 4 Sigma-70, region 4 type 2; KEGG: sme:SMa1550 putative response regulator of two-component system. | 0.580 |
| Meso_0595 | Meso_0599 | Periplasmic sensor diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: conserved hypothetical protein EAL CHASE4; KEGG: sme:SMa0137 putative kinase/esterase. | PFAM: histidine kinase, HAMP region chemotaxis sensory transducer; KEGG: sme:SMa1556 putative methyl-accepting chemotaxis protein. | 0.571 |
| Meso_0595 | Meso_0600 | Periplasmic sensor diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: conserved hypothetical protein EAL CHASE4; KEGG: sme:SMa0137 putative kinase/esterase. | CheA signal transduction histidine kinase; PFAM: response regulator receiver CheW-like protein ATP-binding region, ATPase-like Hpt; KEGG: sme:SMa1558 putative histidine kinase, chemotaxis. | 0.693 |
| Meso_0595 | Meso_0601 | Periplasmic sensor diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: conserved hypothetical protein EAL CHASE4; KEGG: sme:SMa0137 putative kinase/esterase. | Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | 0.484 |
| Meso_0595 | Meso_0757 | Periplasmic sensor diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: conserved hypothetical protein EAL CHASE4; KEGG: sme:SMa0137 putative kinase/esterase. | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: bms:BR0481 sensory box/GGDEF domain/EAL domain protein; TIGRFAM: PAS sensor protein diguanylate cyclase; PFAM: conserved hypothetical protein EAL Diverse 7TM receptor, extracellular region 2 Diverse 7TM receptor, transmembrane region PAS fold-3; SMART: PAC motif. | 0.799 |
| Meso_0595 | Meso_1904 | Periplasmic sensor diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: conserved hypothetical protein EAL CHASE4; KEGG: sme:SMa0137 putative kinase/esterase. | KEGG: ret:RHE_PE00024 probable two-component sensor histidine kinase/response regulator hybrid protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver ATP-binding region, ATPase-like histidine kinase A-like PAS fold-3 PAS fold-4 PAS fold; SMART: PAS PAC motif. | 0.631 |
| Meso_0595 | Meso_1942 | Periplasmic sensor diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: conserved hypothetical protein EAL CHASE4; KEGG: sme:SMa0137 putative kinase/esterase. | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver GAF ATP-binding region, ATPase-like histidine kinase A-like; KEGG: ppu:PP3761 sensor histidine kinase/response regulator. | 0.575 |
| Meso_0595 | Meso_2106 | Periplasmic sensor diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: conserved hypothetical protein EAL CHASE4; KEGG: sme:SMa0137 putative kinase/esterase. | Diguanylate phosphodiesterase; PFAM: EAL; KEGG: mlo:mll2537 hypothetical protein. | 0.492 |
| Meso_0595 | Meso_2467 | Periplasmic sensor diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: conserved hypothetical protein EAL CHASE4; KEGG: sme:SMa0137 putative kinase/esterase. | TIGRFAM: diguanylate cyclase; PFAM: conserved hypothetical protein; KEGG: rpa:RPA2984 putative diguanylate cyclase (GGDEF). | 0.487 |
| Meso_0595 | Meso_3680 | Periplasmic sensor diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: conserved hypothetical protein EAL CHASE4; KEGG: sme:SMa0137 putative kinase/esterase. | Multi-sensor hybrid histidine kinase; KEGG: mlo:mlr3215 two-component sensor/response regulator hybrid; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver ATP-binding region, ATPase-like histidine kinase A-like PAS fold-4; SMART: PAS. | 0.604 |
| Meso_0596 | Meso_0595 | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR response regulator receiver sigma-70 region 4 Sigma-70, region 4 type 2; KEGG: sme:SMa1550 putative response regulator of two-component system. | Periplasmic sensor diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: conserved hypothetical protein EAL CHASE4; KEGG: sme:SMa0137 putative kinase/esterase. | 0.580 |
| Meso_0596 | Meso_0599 | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR response regulator receiver sigma-70 region 4 Sigma-70, region 4 type 2; KEGG: sme:SMa1550 putative response regulator of two-component system. | PFAM: histidine kinase, HAMP region chemotaxis sensory transducer; KEGG: sme:SMa1556 putative methyl-accepting chemotaxis protein. | 0.563 |
| Meso_0596 | Meso_0600 | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR response regulator receiver sigma-70 region 4 Sigma-70, region 4 type 2; KEGG: sme:SMa1550 putative response regulator of two-component system. | CheA signal transduction histidine kinase; PFAM: response regulator receiver CheW-like protein ATP-binding region, ATPase-like Hpt; KEGG: sme:SMa1558 putative histidine kinase, chemotaxis. | 0.823 |
| Meso_0596 | Meso_0601 | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR response regulator receiver sigma-70 region 4 Sigma-70, region 4 type 2; KEGG: sme:SMa1550 putative response regulator of two-component system. | Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. | 0.569 |
| Meso_0596 | Meso_0757 | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR response regulator receiver sigma-70 region 4 Sigma-70, region 4 type 2; KEGG: sme:SMa1550 putative response regulator of two-component system. | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: bms:BR0481 sensory box/GGDEF domain/EAL domain protein; TIGRFAM: PAS sensor protein diguanylate cyclase; PFAM: conserved hypothetical protein EAL Diverse 7TM receptor, extracellular region 2 Diverse 7TM receptor, transmembrane region PAS fold-3; SMART: PAC motif. | 0.532 |
| Meso_0596 | Meso_1942 | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR response regulator receiver sigma-70 region 4 Sigma-70, region 4 type 2; KEGG: sme:SMa1550 putative response regulator of two-component system. | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver GAF ATP-binding region, ATPase-like histidine kinase A-like; KEGG: ppu:PP3761 sensor histidine kinase/response regulator. | 0.886 |
| Meso_0596 | Meso_3680 | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR response regulator receiver sigma-70 region 4 Sigma-70, region 4 type 2; KEGG: sme:SMa1550 putative response regulator of two-component system. | Multi-sensor hybrid histidine kinase; KEGG: mlo:mlr3215 two-component sensor/response regulator hybrid; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver ATP-binding region, ATPase-like histidine kinase A-like PAS fold-4; SMART: PAS. | 0.557 |
| Meso_0599 | Meso_0595 | PFAM: histidine kinase, HAMP region chemotaxis sensory transducer; KEGG: sme:SMa1556 putative methyl-accepting chemotaxis protein. | Periplasmic sensor diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: conserved hypothetical protein EAL CHASE4; KEGG: sme:SMa0137 putative kinase/esterase. | 0.571 |
| Meso_0599 | Meso_0596 | PFAM: histidine kinase, HAMP region chemotaxis sensory transducer; KEGG: sme:SMa1556 putative methyl-accepting chemotaxis protein. | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR response regulator receiver sigma-70 region 4 Sigma-70, region 4 type 2; KEGG: sme:SMa1550 putative response regulator of two-component system. | 0.563 |
| Meso_0599 | Meso_0600 | PFAM: histidine kinase, HAMP region chemotaxis sensory transducer; KEGG: sme:SMa1556 putative methyl-accepting chemotaxis protein. | CheA signal transduction histidine kinase; PFAM: response regulator receiver CheW-like protein ATP-binding region, ATPase-like Hpt; KEGG: sme:SMa1558 putative histidine kinase, chemotaxis. | 0.999 |
