Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Meso_0596Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR response regulator receiver sigma-70 region 4 Sigma-70, region 4 type 2; KEGG: sme:SMa1550 putative response regulator of two-component system. (228 aa)    
Predicted Functional Partners:
Meso_1942
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver GAF ATP-binding region, ATPase-like histidine kinase A-like; KEGG: ppu:PP3761 sensor histidine kinase/response regulator.
  
 
 0.886
Meso_0600
CheA signal transduction histidine kinase; PFAM: response regulator receiver CheW-like protein ATP-binding region, ATPase-like Hpt; KEGG: sme:SMa1558 putative histidine kinase, chemotaxis.
  
 
 0.823
Meso_0795
Histidine kinase; PFAM: ATP-binding region, ATPase-like; KEGG: sme:SMb21519 putative two-component sensor histidine kinase protein.
 
 
 0.815
Meso_0797
PFAM: response regulator receiver; KEGG: ret:RHE_CH01734 probable two-component response regulator protein.
  
     0.744
Meso_0090
Periplasmic sensor hybrid histidine kinase; PFAM: response regulator receiver ATP-binding region, ATPase-like histidine kinase A-like PAS fold-4; KEGG: mlo:mll5691 two-component sensor histidine kinase.
 
 
 0.710
Meso_0340
Periplasmic sensor hybrid histidine kinase; PFAM: response regulator receiver ATP-binding region, ATPase-like histidine kinase, HAMP region histidine kinase A-like; KEGG: bja:bll7016 two-component hybrid sensor and regulator.
 
 
 0.706
Meso_0598
PFAM: CheW-like protein; KEGG: sme:SMa1554 putative purine-binding chemotaxis protein CheW.
 
   
 0.617
Meso_0595
Periplasmic sensor diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: conserved hypothetical protein EAL CHASE4; KEGG: sme:SMa0137 putative kinase/esterase.
 
 
 0.580
Meso_0601
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
     
 0.569
Meso_0599
PFAM: histidine kinase, HAMP region chemotaxis sensory transducer; KEGG: sme:SMa1556 putative methyl-accepting chemotaxis protein.
     
 0.563
Your Current Organism:
Chelativorans sp. BNC1
NCBI taxonomy Id: 266779
Other names: C. sp. BNC1, Mesorhizobium sp. BNC1
Server load: medium (44%) [HD]