Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
thrBTIGRFAM: homoserine kinase; PFAM: aminoglycoside phosphotransferase; KEGG: mlo:mlr7503 homoserine kinase; Belongs to the pseudomonas-type ThrB family. (322 aa)    
Predicted Functional Partners:
Meso_1922
PFAM: homoserine dehydrogenase amino acid-binding ACT homoserine dehydrogenase, NAD-binding; KEGG: mlo:mll0934 homoserine dehydrogenase.
 
  
 0.941
Meso_0760
TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: mlo:mll7517 threonine synthase.
    
 0.922
rnhA
RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.838
Meso_0328
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.814
Meso_2643
PFAM: aminotransferase, class I and II Thioredoxin domain; KEGG: bcl:ABC2888 aminotransferase.
   
 
 0.813
metE
Methionine synthase (B12-independent); Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
     
 0.812
Meso_1167
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: mlo:mlr8465 O-acetylhomoserine (thiol)-lyase.
    
  0.810
Meso_3736
PFAM: aminotransferase, class I and II; KEGG: dde:Dde_0276 aminotransferase, classes I and II.
   
 
  0.810
ilvE
Branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
   
 
 0.807
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
  0.805
Your Current Organism:
Chelativorans sp. BNC1
NCBI taxonomy Id: 266779
Other names: C. sp. BNC1, Mesorhizobium sp. BNC1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.