| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_0456 | Meso_0836 | Meso_0456 | Meso_0836 | Mannose-6-phosphate isomerase, type 2; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase, type II Nucleotidyl transferase Cupin 2, conserved barrel; KEGG: bms:BRA0347 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. | PfkB; PFAM: PfkB; KEGG: rsp:RSP_2257 putative fructokinase; Belongs to the carbohydrate kinase PfkB family. | 0.922 |
| Meso_0456 | Meso_0989 | Meso_0456 | Meso_0989 | Mannose-6-phosphate isomerase, type 2; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase, type II Nucleotidyl transferase Cupin 2, conserved barrel; KEGG: bms:BRA0347 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. | TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX; KEGG: bmb:BruAb1_1274 GlpX protein. | 0.915 |
| Meso_0456 | Meso_1508 | Meso_0456 | Meso_1508 | Mannose-6-phosphate isomerase, type 2; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase, type II Nucleotidyl transferase Cupin 2, conserved barrel; KEGG: bms:BRA0347 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. | TIGRFAM: glucosamine-6-phosphate isomerase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: rba:RB2532 glucosamine-6-phosphate isomerase. | 0.918 |
| Meso_0456 | Meso_2864 | Meso_0456 | Meso_2864 | Mannose-6-phosphate isomerase, type 2; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase, type II Nucleotidyl transferase Cupin 2, conserved barrel; KEGG: bms:BRA0347 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. | Glutamine--fructose-6-phosphate transaminase; PFAM: sugar isomerase (SIS); KEGG: ret:RHE_CH04036 glucosamine--fructose-6-phosphate aminotransferase protein. | 0.905 |
| Meso_0456 | glmS | Meso_0456 | Meso_1706 | Mannose-6-phosphate isomerase, type 2; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase, type II Nucleotidyl transferase Cupin 2, conserved barrel; KEGG: bms:BRA0347 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.922 |
| Meso_0456 | pfp | Meso_0456 | Meso_3467 | Mannose-6-phosphate isomerase, type 2; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase, type II Nucleotidyl transferase Cupin 2, conserved barrel; KEGG: bms:BRA0347 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.927 |
| Meso_0456 | pgi | Meso_0456 | Meso_0070 | Mannose-6-phosphate isomerase, type 2; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase, type II Nucleotidyl transferase Cupin 2, conserved barrel; KEGG: bms:BRA0347 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. | PFAM: phosphoglucose isomerase (PGI); KEGG: sme:SMc02163 probable glucose-6-phosphate isomerase protein. | 0.960 |
| Meso_0456 | xylA | Meso_0456 | Meso_2820 | Mannose-6-phosphate isomerase, type 2; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase, type II Nucleotidyl transferase Cupin 2, conserved barrel; KEGG: bms:BRA0347 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. | TIGRFAM: xylose isomerase; PFAM: Xylose isomerase-like TIM barrel; KEGG: mlo:mlr5036 xylose isomerase; Belongs to the xylose isomerase family. | 0.415 |
| Meso_0836 | Meso_0456 | Meso_0836 | Meso_0456 | PfkB; PFAM: PfkB; KEGG: rsp:RSP_2257 putative fructokinase; Belongs to the carbohydrate kinase PfkB family. | Mannose-6-phosphate isomerase, type 2; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase, type II Nucleotidyl transferase Cupin 2, conserved barrel; KEGG: bms:BRA0347 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. | 0.922 |
| Meso_0836 | Meso_0989 | Meso_0836 | Meso_0989 | PfkB; PFAM: PfkB; KEGG: rsp:RSP_2257 putative fructokinase; Belongs to the carbohydrate kinase PfkB family. | TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX; KEGG: bmb:BruAb1_1274 GlpX protein. | 0.909 |
| Meso_0836 | Meso_1508 | Meso_0836 | Meso_1508 | PfkB; PFAM: PfkB; KEGG: rsp:RSP_2257 putative fructokinase; Belongs to the carbohydrate kinase PfkB family. | TIGRFAM: glucosamine-6-phosphate isomerase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: rba:RB2532 glucosamine-6-phosphate isomerase. | 0.909 |
| Meso_0836 | Meso_2864 | Meso_0836 | Meso_2864 | PfkB; PFAM: PfkB; KEGG: rsp:RSP_2257 putative fructokinase; Belongs to the carbohydrate kinase PfkB family. | Glutamine--fructose-6-phosphate transaminase; PFAM: sugar isomerase (SIS); KEGG: ret:RHE_CH04036 glucosamine--fructose-6-phosphate aminotransferase protein. | 0.920 |
| Meso_0836 | Meso_3687 | Meso_0836 | Meso_3687 | PfkB; PFAM: PfkB; KEGG: rsp:RSP_2257 putative fructokinase; Belongs to the carbohydrate kinase PfkB family. | PFAM: alpha amylase, catalytic region; SMART: Alpha amylase, catalytic subdomain; KEGG: rpa:RPA4759 glycosyl hydrolase, family 13. | 0.925 |
| Meso_0836 | Meso_3701 | Meso_0836 | Meso_3701 | PfkB; PFAM: PfkB; KEGG: rsp:RSP_2257 putative fructokinase; Belongs to the carbohydrate kinase PfkB family. | PFAM: Alcohol dehydrogenase, zinc-binding Alcohol dehydrogenase GroES-like; KEGG: oih:OB2752 sorbitol dehydrogenase. | 0.907 |
| Meso_0836 | glmS | Meso_0836 | Meso_1706 | PfkB; PFAM: PfkB; KEGG: rsp:RSP_2257 putative fructokinase; Belongs to the carbohydrate kinase PfkB family. | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.915 |
| Meso_0836 | pfp | Meso_0836 | Meso_3467 | PfkB; PFAM: PfkB; KEGG: rsp:RSP_2257 putative fructokinase; Belongs to the carbohydrate kinase PfkB family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.921 |
| Meso_0836 | pgi | Meso_0836 | Meso_0070 | PfkB; PFAM: PfkB; KEGG: rsp:RSP_2257 putative fructokinase; Belongs to the carbohydrate kinase PfkB family. | PFAM: phosphoglucose isomerase (PGI); KEGG: sme:SMc02163 probable glucose-6-phosphate isomerase protein. | 0.928 |
| Meso_0836 | xylA | Meso_0836 | Meso_2820 | PfkB; PFAM: PfkB; KEGG: rsp:RSP_2257 putative fructokinase; Belongs to the carbohydrate kinase PfkB family. | TIGRFAM: xylose isomerase; PFAM: Xylose isomerase-like TIM barrel; KEGG: mlo:mlr5036 xylose isomerase; Belongs to the xylose isomerase family. | 0.916 |
| Meso_0989 | Meso_0456 | Meso_0989 | Meso_0456 | TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX; KEGG: bmb:BruAb1_1274 GlpX protein. | Mannose-6-phosphate isomerase, type 2; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase, type II Nucleotidyl transferase Cupin 2, conserved barrel; KEGG: bms:BRA0347 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase. | 0.915 |
| Meso_0989 | Meso_0836 | Meso_0989 | Meso_0836 | TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX; KEGG: bmb:BruAb1_1274 GlpX protein. | PfkB; PFAM: PfkB; KEGG: rsp:RSP_2257 putative fructokinase; Belongs to the carbohydrate kinase PfkB family. | 0.909 |
