Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Meso_0902Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver transcriptional regulatory protein-like; KEGG: mlo:mlr7695 two-component response regulator. (224 aa)    
Predicted Functional Partners:
Meso_0903
Periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like histidine kinase, HAMP region histidine kinase A-like; KEGG: mlo:mlr7697 two-component, sensor histidine kinase.
 
 0.974
Meso_1942
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver GAF ATP-binding region, ATPase-like histidine kinase A-like; KEGG: ppu:PP3761 sensor histidine kinase/response regulator.
  
 
 0.884
Meso_0600
CheA signal transduction histidine kinase; PFAM: response regulator receiver CheW-like protein ATP-binding region, ATPase-like Hpt; KEGG: sme:SMa1558 putative histidine kinase, chemotaxis.
 
 
 0.870
Meso_3680
Multi-sensor hybrid histidine kinase; KEGG: mlo:mlr3215 two-component sensor/response regulator hybrid; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver ATP-binding region, ATPase-like histidine kinase A-like PAS fold-4; SMART: PAS.
 
 
0.832
Meso_0905
Multi-sensor signal transduction histidine kinase; KEGG: bmb:BruAb1_0635 histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase-like histidine kinase A-like PAS fold-3; SMART: PAS PAC motif.
 
 
 0.788
Meso_0171
KEGG: mlo:mll6540 two component histidine protein kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase-like histidine kinase A-like PAS fold-4 PAS fold; SMART: PAS.
 
 
 0.786
Meso_1740
Cell cycle control histidine kinase CckA; KEGG: mlo:mll0767 sensor kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver ATP-binding region, ATPase-like histidine kinase A-like PAS fold-4 PAS fold; SMART: PAS.
 
 
 0.786
Meso_1904
KEGG: ret:RHE_PE00024 probable two-component sensor histidine kinase/response regulator hybrid protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver ATP-binding region, ATPase-like histidine kinase A-like PAS fold-3 PAS fold-4 PAS fold; SMART: PAS PAC motif.
 
 
 0.774
Meso_3577
PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like histidine kinase A-like; SMART: PAS; KEGG: mlo:mll5087 two-component sensor histidine kinase.
 
 
 0.747
glnE
Glutamate-ammonia ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...]
     
 0.725
Your Current Organism:
Chelativorans sp. BNC1
NCBI taxonomy Id: 266779
Other names: C. sp. BNC1, Mesorhizobium sp. BNC1
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