| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_0541 | Meso_0949 | Meso_0541 | Meso_0949 | PFAM: SNF2-related helicase-like type III restriction enzyme, res subunit; SMART: DEAD/DEAH box helicase-like; KEGG: ecc:c5378 hypothetical protein. | Signal peptidase I. Serine peptidase. MEROPS family S26A; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; KEGG: mlo:mlr7763 signal peptidase I; Belongs to the peptidase S26 family. | 0.700 |
| Meso_0946 | Meso_0949 | Meso_0946 | Meso_0949 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Signal peptidase I. Serine peptidase. MEROPS family S26A; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; KEGG: mlo:mlr7763 signal peptidase I; Belongs to the peptidase S26 family. | 0.691 |
| Meso_0946 | era | Meso_0946 | Meso_0951 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.717 |
| Meso_0946 | recO | Meso_0946 | Meso_0952 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.496 |
| Meso_0946 | rnc | Meso_0946 | Meso_0950 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.499 |
| Meso_0946 | rnhB | Meso_0946 | Meso_0703 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.489 |
| Meso_0949 | Meso_0541 | Meso_0949 | Meso_0541 | Signal peptidase I. Serine peptidase. MEROPS family S26A; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; KEGG: mlo:mlr7763 signal peptidase I; Belongs to the peptidase S26 family. | PFAM: SNF2-related helicase-like type III restriction enzyme, res subunit; SMART: DEAD/DEAH box helicase-like; KEGG: ecc:c5378 hypothetical protein. | 0.700 |
| Meso_0949 | Meso_0946 | Meso_0949 | Meso_0946 | Signal peptidase I. Serine peptidase. MEROPS family S26A; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; KEGG: mlo:mlr7763 signal peptidase I; Belongs to the peptidase S26 family. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.691 |
| Meso_0949 | era | Meso_0949 | Meso_0951 | Signal peptidase I. Serine peptidase. MEROPS family S26A; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; KEGG: mlo:mlr7763 signal peptidase I; Belongs to the peptidase S26 family. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.859 |
| Meso_0949 | lepA | Meso_0949 | Meso_4075 | Signal peptidase I. Serine peptidase. MEROPS family S26A; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; KEGG: mlo:mlr7763 signal peptidase I; Belongs to the peptidase S26 family. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.798 |
| Meso_0949 | minE | Meso_0949 | Meso_0321 | Signal peptidase I. Serine peptidase. MEROPS family S26A; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; KEGG: mlo:mlr7763 signal peptidase I; Belongs to the peptidase S26 family. | Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. | 0.675 |
| Meso_0949 | recO | Meso_0949 | Meso_0952 | Signal peptidase I. Serine peptidase. MEROPS family S26A; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; KEGG: mlo:mlr7763 signal peptidase I; Belongs to the peptidase S26 family. | DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.858 |
| Meso_0949 | rnc | Meso_0949 | Meso_0950 | Signal peptidase I. Serine peptidase. MEROPS family S26A; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; KEGG: mlo:mlr7763 signal peptidase I; Belongs to the peptidase S26 family. | RNAse III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.939 |
| Meso_0949 | rnhB | Meso_0949 | Meso_0703 | Signal peptidase I. Serine peptidase. MEROPS family S26A; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; KEGG: mlo:mlr7763 signal peptidase I; Belongs to the peptidase S26 family. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.737 |
| Meso_0949 | secF | Meso_0949 | Meso_1796 | Signal peptidase I. Serine peptidase. MEROPS family S26A; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; KEGG: mlo:mlr7763 signal peptidase I; Belongs to the peptidase S26 family. | Protein translocase subunit secD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.757 |
| Meso_0949 | yidC | Meso_0949 | Meso_0376 | Signal peptidase I. Serine peptidase. MEROPS family S26A; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; KEGG: mlo:mlr7763 signal peptidase I; Belongs to the peptidase S26 family. | Protein translocase subunit yidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.726 |
| era | Meso_0946 | Meso_0951 | Meso_0946 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.717 |
| era | Meso_0949 | Meso_0951 | Meso_0949 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Signal peptidase I. Serine peptidase. MEROPS family S26A; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B; KEGG: mlo:mlr7763 signal peptidase I; Belongs to the peptidase S26 family. | 0.859 |
| era | lepA | Meso_0951 | Meso_4075 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.515 |
| era | recO | Meso_0951 | Meso_0952 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.929 |