Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Meso_1052PFAM: thiamine pyrophosphate enzyme-like TPP-binding; KEGG: bja:blr2858 probable sulfopyruvate decarboxylase. (196 aa)    
Predicted Functional Partners:
Meso_1051
KEGG: bja:bll6809 hypothetical protein.
 
     0.950
Meso_1489
TIGRFAM: acetolactate synthase, small subunit; PFAM: amino acid-binding ACT; KEGG: mlo:mll1432 acetolactate synthase small subunit.
  
 0.821
Meso_1068
KEGG: bja:bll3172 putative sulfopyruvate decarboxylase subunit alpha.
 
     0.791
Meso_0802
KEGG: bbr:BB3568 putative decarboxylase.
 
     0.762
Meso_1053
Succinate semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: atc:AGR_L_2660 hypothetical protein.
  
  0.607
Meso_1050
PFAM: NHL repeat; KEGG: bja:bll1368 hypothetical protein.
 
     0.600
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
  
 0.535
Meso_1054
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: fra:Francci3_1239 short-chain dehydrogenase/reductase SDR.
   
  0.516
Meso_1049
PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: sme:SMc00501 hypothetical protein.
       0.500
Meso_1048
Methylitaconate delta2-delta3-isomerase; PFAM: protein of unknown function DUF453; KEGG: bba:Bd2841 hypothetical protein.
       0.490
Your Current Organism:
Chelativorans sp. BNC1
NCBI taxonomy Id: 266779
Other names: C. sp. BNC1, Mesorhizobium sp. BNC1
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