| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_1132 | Meso_1133 | Meso_1132 | Meso_1133 | PFAM: regulatory protein, MarR; KEGG: mlo:mlr8394 transcriptional regulator. | TIGRFAM: Twin-arginine translocation pathway signal; PFAM: Peptidoglycan-binding domain 1; KEGG: mlo:mlr8397 hypothetical protein. | 0.467 |
| Meso_1133 | Meso_1132 | Meso_1133 | Meso_1132 | TIGRFAM: Twin-arginine translocation pathway signal; PFAM: Peptidoglycan-binding domain 1; KEGG: mlo:mlr8397 hypothetical protein. | PFAM: regulatory protein, MarR; KEGG: mlo:mlr8394 transcriptional regulator. | 0.467 |
| Meso_1133 | Meso_1136 | Meso_1133 | Meso_1136 | TIGRFAM: Twin-arginine translocation pathway signal; PFAM: Peptidoglycan-binding domain 1; KEGG: mlo:mlr8397 hypothetical protein. | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.432 |
| Meso_1133 | Meso_1926 | Meso_1133 | Meso_1926 | TIGRFAM: Twin-arginine translocation pathway signal; PFAM: Peptidoglycan-binding domain 1; KEGG: mlo:mlr8397 hypothetical protein. | Peptidase M15A; PFAM: protein of unknown function DUF882 Peptidase M15A; KEGG: mlo:mlr0938 hypothetical protein. | 0.541 |
| Meso_1133 | Meso_2732 | Meso_1133 | Meso_2732 | TIGRFAM: Twin-arginine translocation pathway signal; PFAM: Peptidoglycan-binding domain 1; KEGG: mlo:mlr8397 hypothetical protein. | PFAM: protein of unknown function DUF882 Peptidase M15A; KEGG: bme:BMEII0010 hypothetical membrane associated protein. | 0.723 |
| Meso_1133 | Meso_3060 | Meso_1133 | Meso_3060 | TIGRFAM: Twin-arginine translocation pathway signal; PFAM: Peptidoglycan-binding domain 1; KEGG: mlo:mlr8397 hypothetical protein. | PFAM: protein of unknown function DUF949; KEGG: mlo:mlr3577 hypothetical protein. | 0.495 |
| Meso_1133 | Meso_3596 | Meso_1133 | Meso_3596 | TIGRFAM: Twin-arginine translocation pathway signal; PFAM: Peptidoglycan-binding domain 1; KEGG: mlo:mlr8397 hypothetical protein. | Murein endopeptidase. Metallo peptidase. MEROPS family M74; PFAM: peptidase U6, penicillin-insensitive murein endopeptidase; KEGG: mlo:mlr4639 penicillin-insensitive murein endopeptidase A. | 0.441 |
| Meso_1133 | glyA | Meso_1133 | Meso_1134 | TIGRFAM: Twin-arginine translocation pathway signal; PFAM: Peptidoglycan-binding domain 1; KEGG: mlo:mlr8397 hypothetical protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.529 |
| Meso_1133 | nrdR | Meso_1133 | Meso_1135 | TIGRFAM: Twin-arginine translocation pathway signal; PFAM: Peptidoglycan-binding domain 1; KEGG: mlo:mlr8397 hypothetical protein. | Ribonucleotide reductase regulator NrdR-like protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.437 |
| Meso_1136 | Meso_1133 | Meso_1136 | Meso_1133 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: Twin-arginine translocation pathway signal; PFAM: Peptidoglycan-binding domain 1; KEGG: mlo:mlr8397 hypothetical protein. | 0.432 |
| Meso_1136 | glyA | Meso_1136 | Meso_1134 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.682 |
| Meso_1136 | nrdR | Meso_1136 | Meso_1135 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Ribonucleotide reductase regulator NrdR-like protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. | 0.882 |
| Meso_1926 | Meso_1133 | Meso_1926 | Meso_1133 | Peptidase M15A; PFAM: protein of unknown function DUF882 Peptidase M15A; KEGG: mlo:mlr0938 hypothetical protein. | TIGRFAM: Twin-arginine translocation pathway signal; PFAM: Peptidoglycan-binding domain 1; KEGG: mlo:mlr8397 hypothetical protein. | 0.541 |
| Meso_2732 | Meso_1133 | Meso_2732 | Meso_1133 | PFAM: protein of unknown function DUF882 Peptidase M15A; KEGG: bme:BMEII0010 hypothetical membrane associated protein. | TIGRFAM: Twin-arginine translocation pathway signal; PFAM: Peptidoglycan-binding domain 1; KEGG: mlo:mlr8397 hypothetical protein. | 0.723 |
| Meso_2732 | Meso_3060 | Meso_2732 | Meso_3060 | PFAM: protein of unknown function DUF882 Peptidase M15A; KEGG: bme:BMEII0010 hypothetical membrane associated protein. | PFAM: protein of unknown function DUF949; KEGG: mlo:mlr3577 hypothetical protein. | 0.620 |
| Meso_2732 | Meso_3596 | Meso_2732 | Meso_3596 | PFAM: protein of unknown function DUF882 Peptidase M15A; KEGG: bme:BMEII0010 hypothetical membrane associated protein. | Murein endopeptidase. Metallo peptidase. MEROPS family M74; PFAM: peptidase U6, penicillin-insensitive murein endopeptidase; KEGG: mlo:mlr4639 penicillin-insensitive murein endopeptidase A. | 0.705 |
| Meso_3060 | Meso_1133 | Meso_3060 | Meso_1133 | PFAM: protein of unknown function DUF949; KEGG: mlo:mlr3577 hypothetical protein. | TIGRFAM: Twin-arginine translocation pathway signal; PFAM: Peptidoglycan-binding domain 1; KEGG: mlo:mlr8397 hypothetical protein. | 0.495 |
| Meso_3060 | Meso_2732 | Meso_3060 | Meso_2732 | PFAM: protein of unknown function DUF949; KEGG: mlo:mlr3577 hypothetical protein. | PFAM: protein of unknown function DUF882 Peptidase M15A; KEGG: bme:BMEII0010 hypothetical membrane associated protein. | 0.620 |
| Meso_3060 | Meso_3596 | Meso_3060 | Meso_3596 | PFAM: protein of unknown function DUF949; KEGG: mlo:mlr3577 hypothetical protein. | Murein endopeptidase. Metallo peptidase. MEROPS family M74; PFAM: peptidase U6, penicillin-insensitive murein endopeptidase; KEGG: mlo:mlr4639 penicillin-insensitive murein endopeptidase A. | 0.474 |
| Meso_3596 | Meso_1133 | Meso_3596 | Meso_1133 | Murein endopeptidase. Metallo peptidase. MEROPS family M74; PFAM: peptidase U6, penicillin-insensitive murein endopeptidase; KEGG: mlo:mlr4639 penicillin-insensitive murein endopeptidase A. | TIGRFAM: Twin-arginine translocation pathway signal; PFAM: Peptidoglycan-binding domain 1; KEGG: mlo:mlr8397 hypothetical protein. | 0.441 |
