| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_1336 | Meso_1373 | Meso_1336 | Meso_1373 | PFAM: peptidase S14, ClpP; KEGG: pae:PA3326 probable Clp-family ATP-dependent protease; Belongs to the peptidase S14 family. | KEGG: mlo:mll0663 endopeptidase Clp ATP-binding chain A; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central region Clp, N terminal ATPase associated with various cellular activities, AAA_5 ATPase AAA-2; SMART: ATPase; Belongs to the ClpA/ClpB family. | 0.870 |
| Meso_1336 | clpB | Meso_1336 | Meso_2996 | PFAM: peptidase S14, ClpP; KEGG: pae:PA3326 probable Clp-family ATP-dependent protease; Belongs to the peptidase S14 family. | ATPase AAA-2; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.870 |
| Meso_1336 | clpX | Meso_1336 | Meso_1170 | PFAM: peptidase S14, ClpP; KEGG: pae:PA3326 probable Clp-family ATP-dependent protease; Belongs to the peptidase S14 family. | ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.960 |
| Meso_1336 | hslU | Meso_1336 | Meso_3490 | PFAM: peptidase S14, ClpP; KEGG: pae:PA3326 probable Clp-family ATP-dependent protease; Belongs to the peptidase S14 family. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.553 |
| Meso_1336 | hslV | Meso_1336 | Meso_3492 | PFAM: peptidase S14, ClpP; KEGG: pae:PA3326 probable Clp-family ATP-dependent protease; Belongs to the peptidase S14 family. | HslV component of HslUV peptidase. Threonine peptidase. MEROPS family T01B; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.621 |
| Meso_1336 | lon | Meso_1336 | Meso_1171 | PFAM: peptidase S14, ClpP; KEGG: pae:PA3326 probable Clp-family ATP-dependent protease; Belongs to the peptidase S14 family. | ATP-dependent proteinase. Serine peptidase. MEROPS family S16; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.541 |
| Meso_1373 | Meso_1336 | Meso_1373 | Meso_1336 | KEGG: mlo:mll0663 endopeptidase Clp ATP-binding chain A; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central region Clp, N terminal ATPase associated with various cellular activities, AAA_5 ATPase AAA-2; SMART: ATPase; Belongs to the ClpA/ClpB family. | PFAM: peptidase S14, ClpP; KEGG: pae:PA3326 probable Clp-family ATP-dependent protease; Belongs to the peptidase S14 family. | 0.870 |
| Meso_1373 | clpP1 | Meso_1373 | Meso_1169 | KEGG: mlo:mll0663 endopeptidase Clp ATP-binding chain A; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central region Clp, N terminal ATPase associated with various cellular activities, AAA_5 ATPase AAA-2; SMART: ATPase; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.898 |
| Meso_1373 | clpP2 | Meso_1373 | Meso_1531 | KEGG: mlo:mll0663 endopeptidase Clp ATP-binding chain A; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central region Clp, N terminal ATPase associated with various cellular activities, AAA_5 ATPase AAA-2; SMART: ATPase; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.898 |
| Meso_1373 | clpX | Meso_1373 | Meso_1170 | KEGG: mlo:mll0663 endopeptidase Clp ATP-binding chain A; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central region Clp, N terminal ATPase associated with various cellular activities, AAA_5 ATPase AAA-2; SMART: ATPase; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.796 |
| Meso_1373 | ftsH | Meso_1373 | Meso_3167 | KEGG: mlo:mll0663 endopeptidase Clp ATP-binding chain A; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central region Clp, N terminal ATPase associated with various cellular activities, AAA_5 ATPase AAA-2; SMART: ATPase; Belongs to the ClpA/ClpB family. | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.550 |
| Meso_1373 | hslU | Meso_1373 | Meso_3490 | KEGG: mlo:mll0663 endopeptidase Clp ATP-binding chain A; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central region Clp, N terminal ATPase associated with various cellular activities, AAA_5 ATPase AAA-2; SMART: ATPase; Belongs to the ClpA/ClpB family. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.652 |
| Meso_1373 | hslV | Meso_1373 | Meso_3492 | KEGG: mlo:mll0663 endopeptidase Clp ATP-binding chain A; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central region Clp, N terminal ATPase associated with various cellular activities, AAA_5 ATPase AAA-2; SMART: ATPase; Belongs to the ClpA/ClpB family. | HslV component of HslUV peptidase. Threonine peptidase. MEROPS family T01B; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.492 |
| Meso_1373 | lon | Meso_1373 | Meso_1171 | KEGG: mlo:mll0663 endopeptidase Clp ATP-binding chain A; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central region Clp, N terminal ATPase associated with various cellular activities, AAA_5 ATPase AAA-2; SMART: ATPase; Belongs to the ClpA/ClpB family. | ATP-dependent proteinase. Serine peptidase. MEROPS family S16; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.715 |
| atpD | clpX | Meso_3218 | Meso_1170 | ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.799 |
| atpD | ftsH | Meso_3218 | Meso_3167 | ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.504 |
| atpD | lon | Meso_3218 | Meso_1171 | ATP synthase F1 subcomplex beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | ATP-dependent proteinase. Serine peptidase. MEROPS family S16; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.614 |
| clpB | Meso_1336 | Meso_2996 | Meso_1336 | ATPase AAA-2; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | PFAM: peptidase S14, ClpP; KEGG: pae:PA3326 probable Clp-family ATP-dependent protease; Belongs to the peptidase S14 family. | 0.870 |
| clpB | clpP1 | Meso_2996 | Meso_1169 | ATPase AAA-2; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.905 |
| clpB | clpP2 | Meso_2996 | Meso_1531 | ATPase AAA-2; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.905 |
