| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_0034 | murD | Meso_0034 | Meso_2009 | PFAM: protein of unknown function DUF1611; KEGG: jan:Jann_0366 protein of unknown function DUF1611. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.900 |
| Meso_0034 | murI | Meso_0034 | Meso_1269 | PFAM: protein of unknown function DUF1611; KEGG: jan:Jann_0366 protein of unknown function DUF1611. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.900 |
| Meso_0034 | purQ | Meso_0034 | Meso_1279 | PFAM: protein of unknown function DUF1611; KEGG: jan:Jann_0366 protein of unknown function DUF1611. | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.900 |
| Meso_0161 | Meso_1325 | Meso_0161 | Meso_1325 | PFAM: glutamine synthetase, catalytic region; KEGG: bms:BRA0768 glutamine synthetase family protein. | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.935 |
| Meso_0161 | Meso_1544 | Meso_0161 | Meso_1544 | PFAM: glutamine synthetase, catalytic region; KEGG: bms:BRA0768 glutamine synthetase family protein. | TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region glutamine synthetase, beta-Grasp; KEGG: sme:SMc00948 glutamine synthetase I protein. | 0.921 |
| Meso_0161 | Meso_1870 | Meso_0161 | Meso_1870 | PFAM: glutamine synthetase, catalytic region; KEGG: bms:BRA0768 glutamine synthetase family protein. | PFAM: glutamine synthetase, catalytic region; KEGG: sme:SMc01594 probable glutamine synthetase. | 0.918 |
| Meso_0161 | Meso_2744 | Meso_0161 | Meso_2744 | PFAM: glutamine synthetase, catalytic region; KEGG: bms:BRA0768 glutamine synthetase family protein. | PFAM: glutamine amidotransferase, class-II glutamate synthase, alpha subunit-like ferredoxin-dependent glutamate synthase glutamate synthase; KEGG: mlo:mll3030 glutamate synthase (NADPH) large chain. | 0.964 |
| Meso_0161 | Meso_3422 | Meso_0161 | Meso_3422 | PFAM: glutamine synthetase, catalytic region; KEGG: bms:BRA0768 glutamine synthetase family protein. | PFAM: NAD-glutamate dehydrogenase; KEGG: mlo:mll4104 hypothetical protein. | 0.910 |
| Meso_0161 | murI | Meso_0161 | Meso_1269 | PFAM: glutamine synthetase, catalytic region; KEGG: bms:BRA0768 glutamine synthetase family protein. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.829 |
| Meso_0161 | purQ | Meso_0161 | Meso_1279 | PFAM: glutamine synthetase, catalytic region; KEGG: bms:BRA0768 glutamine synthetase family protein. | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.906 |
| Meso_1325 | Meso_0161 | Meso_1325 | Meso_0161 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | PFAM: glutamine synthetase, catalytic region; KEGG: bms:BRA0768 glutamine synthetase family protein. | 0.935 |
| Meso_1325 | Meso_1428 | Meso_1325 | Meso_1428 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | TIGRFAM: alanine dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding alanine dehydrogenase/PNT-like; KEGG: mlo:mll9089 alanine dehydrogenase; Belongs to the AlaDH/PNT family. | 0.623 |
| Meso_1325 | Meso_1544 | Meso_1325 | Meso_1544 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase, catalytic region glutamine synthetase, beta-Grasp; KEGG: sme:SMc00948 glutamine synthetase I protein. | 0.935 |
| Meso_1325 | Meso_1870 | Meso_1325 | Meso_1870 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | PFAM: glutamine synthetase, catalytic region; KEGG: sme:SMc01594 probable glutamine synthetase. | 0.935 |
| Meso_1325 | Meso_2744 | Meso_1325 | Meso_2744 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | PFAM: glutamine amidotransferase, class-II glutamate synthase, alpha subunit-like ferredoxin-dependent glutamate synthase glutamate synthase; KEGG: mlo:mll3030 glutamate synthase (NADPH) large chain. | 0.948 |
| Meso_1325 | Meso_3422 | Meso_1325 | Meso_3422 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | PFAM: NAD-glutamate dehydrogenase; KEGG: mlo:mll4104 hypothetical protein. | 0.922 |
| Meso_1325 | murI | Meso_1325 | Meso_1269 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.870 |
| Meso_1325 | purQ | Meso_1325 | Meso_1279 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | Phosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] | 0.902 |
| Meso_1428 | Meso_1325 | Meso_1428 | Meso_1325 | TIGRFAM: alanine dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding alanine dehydrogenase/PNT-like; KEGG: mlo:mll9089 alanine dehydrogenase; Belongs to the AlaDH/PNT family. | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.623 |
| Meso_1428 | Meso_2744 | Meso_1428 | Meso_2744 | TIGRFAM: alanine dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding alanine dehydrogenase/PNT-like; KEGG: mlo:mll9089 alanine dehydrogenase; Belongs to the AlaDH/PNT family. | PFAM: glutamine amidotransferase, class-II glutamate synthase, alpha subunit-like ferredoxin-dependent glutamate synthase glutamate synthase; KEGG: mlo:mll3030 glutamate synthase (NADPH) large chain. | 0.446 |