| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_0662 | Meso_1136 | Meso_0662 | Meso_1136 | TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase, middle region; KEGG: mlo:mlr5076 folylpolyglutamate synthase / dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.524 |
| Meso_0662 | Meso_1412 | Meso_0662 | Meso_1412 | TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase, middle region; KEGG: mlo:mlr5076 folylpolyglutamate synthase / dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.997 |
| Meso_0662 | Meso_1413 | Meso_0662 | Meso_1413 | TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase, middle region; KEGG: mlo:mlr5076 folylpolyglutamate synthase / dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.695 |
| Meso_0662 | Meso_1414 | Meso_0662 | Meso_1414 | TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase, middle region; KEGG: mlo:mlr5076 folylpolyglutamate synthase / dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: mlo:mll0786 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | 0.737 |
| Meso_0662 | Meso_2199 | Meso_0662 | Meso_2199 | TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase, middle region; KEGG: mlo:mlr5076 folylpolyglutamate synthase / dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | TIGRFAM: glutamine amidotransferase of anthranilate synthase anthranilate synthase; PFAM: glutamine amidotransferase class-I Anthranilate synthase component I and chorismate binding protein Anthranilate synthase component I-like; KEGG: mlo:mlr2774 anthranilate synthase. | 0.579 |
| Meso_0662 | folE | Meso_0662 | Meso_1004 | TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase, middle region; KEGG: mlo:mlr5076 folylpolyglutamate synthase / dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | PFAM: GTP cyclohydrolase I; KEGG: mlo:mlr0922 GTP cyclohydrolase I. | 0.691 |
| Meso_0662 | ribB | Meso_0662 | Meso_0731 | TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase, middle region; KEGG: mlo:mlr5076 folylpolyglutamate synthase / dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.447 |
| Meso_1136 | Meso_0662 | Meso_1136 | Meso_0662 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase, middle region; KEGG: mlo:mlr5076 folylpolyglutamate synthase / dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | 0.524 |
| Meso_1136 | Meso_1412 | Meso_1136 | Meso_1412 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.781 |
| Meso_1136 | Meso_1413 | Meso_1136 | Meso_1413 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.701 |
| Meso_1136 | Meso_1414 | Meso_1136 | Meso_1414 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: mlo:mll0786 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | 0.769 |
| Meso_1136 | Meso_2176 | Meso_1136 | Meso_2176 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | PFAM: Polynucleotide adenylyltransferase region; KEGG: mlo:mll2726 tRNA nucleotidyltransferase (CCA-adding enzyme); Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.636 |
| Meso_1136 | Meso_2199 | Meso_1136 | Meso_2199 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: glutamine amidotransferase of anthranilate synthase anthranilate synthase; PFAM: glutamine amidotransferase class-I Anthranilate synthase component I and chorismate binding protein Anthranilate synthase component I-like; KEGG: mlo:mlr2774 anthranilate synthase. | 0.665 |
| Meso_1136 | folE | Meso_1136 | Meso_1004 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | PFAM: GTP cyclohydrolase I; KEGG: mlo:mlr0922 GTP cyclohydrolase I. | 0.598 |
| Meso_1136 | ribB | Meso_1136 | Meso_0731 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.999 |
| Meso_1136 | ribH | Meso_1136 | Meso_1138 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.995 |
| Meso_1411 | Meso_1412 | Meso_1411 | Meso_1412 | PFAM: protein of unknown function DUF922; KEGG: mlo:mlr0789 hypothetical protein. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.585 |
| Meso_1411 | Meso_1413 | Meso_1411 | Meso_1413 | PFAM: protein of unknown function DUF922; KEGG: mlo:mlr0789 hypothetical protein. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.576 |
| Meso_1411 | Meso_1414 | Meso_1411 | Meso_1414 | PFAM: protein of unknown function DUF922; KEGG: mlo:mlr0789 hypothetical protein. | TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: mlo:mll0786 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase. | 0.638 |
| Meso_1412 | Meso_0662 | Meso_1412 | Meso_0662 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase, middle region; KEGG: mlo:mlr5076 folylpolyglutamate synthase / dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family. | 0.997 |