Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Meso_1552PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; KEGG: mlo:mll0563 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase. (323 aa)    
Predicted Functional Partners:
Meso_3989
uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
  
 0.633
Meso_1550
TIGRFAM: conserved hypothetical protein; KEGG: bmb:BruAb1_0876 hypothetical protein.
  
    0.618
Meso_1551
PFAM: protein of unknown function DUF1289; KEGG: mlo:mlr0564 hypothetical protein.
       0.615
Meso_2693
PFAM: Phosphoglycerate mutase; KEGG: sme:SMb20250 hypothetical protein.
 
  
 0.542
Meso_0933
PFAM: aminotransferase, class I and II; KEGG: mlo:mll7737 histidinol-phosphate aminotransferase.
  
  
 0.510
hisC
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase, class I and II; KEGG: mlo:mll3536 imidazole acetol phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
  
 0.510
Meso_3031
TIGRFAM: ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: mlo:mlr3485 hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family.
 
   
 0.478
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
   
 0.467
Meso_1129
Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: mlo:mll8390 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
   
 0.452
Meso_0328
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
     
 0.446
Your Current Organism:
Chelativorans sp. BNC1
NCBI taxonomy Id: 266779
Other names: C. sp. BNC1, Mesorhizobium sp. BNC1
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