| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_0946 | Meso_1611 | Meso_0946 | Meso_1611 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: mlo:mll0404 MazG protein. | 0.928 |
| Meso_1611 | Meso_0946 | Meso_1611 | Meso_0946 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: mlo:mll0404 MazG protein. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.928 |
| Meso_1611 | Meso_1622 | Meso_1611 | Meso_1622 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: mlo:mll0404 MazG protein. | PFAM: CinA-like; KEGG: rpb:RPB_2886 CinA-like; Belongs to the CinA family. | 0.914 |
| Meso_1611 | Meso_2725 | Meso_1611 | Meso_2725 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: mlo:mll0404 MazG protein. | 5'-Nucleotidase-like protein; PFAM: Peptidoglycan-binding LysM metallophosphoesterase 5'-Nucleotidase-like; KEGG: ret:RHE_CH03555 probable 5'-nucleotidase protein; Belongs to the 5'-nucleotidase family. | 0.915 |
| Meso_1611 | Meso_3479 | Meso_1611 | Meso_3479 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: mlo:mll0404 MazG protein. | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily. | 0.916 |
| Meso_1611 | adk | Meso_1611 | Meso_1657 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: mlo:mll0404 MazG protein. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.911 |
| Meso_1611 | nadE-2 | Meso_1611 | Meso_2881 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: mlo:mll0404 MazG protein. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.913 |
| Meso_1611 | pncB | Meso_1611 | Meso_1739 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: mlo:mll0404 MazG protein. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.914 |
| Meso_1611 | pyrG | Meso_1611 | Meso_1634 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: mlo:mll0404 MazG protein. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.911 |
| Meso_1611 | thyA | Meso_1611 | Meso_1751 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: mlo:mll0404 MazG protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.930 |
| Meso_1611 | tmk | Meso_1611 | Meso_1581 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: mlo:mll0404 MazG protein. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.915 |
| Meso_1622 | Meso_1611 | Meso_1622 | Meso_1611 | PFAM: CinA-like; KEGG: rpb:RPB_2886 CinA-like; Belongs to the CinA family. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: mlo:mll0404 MazG protein. | 0.914 |
| Meso_1622 | Meso_2725 | Meso_1622 | Meso_2725 | PFAM: CinA-like; KEGG: rpb:RPB_2886 CinA-like; Belongs to the CinA family. | 5'-Nucleotidase-like protein; PFAM: Peptidoglycan-binding LysM metallophosphoesterase 5'-Nucleotidase-like; KEGG: ret:RHE_CH03555 probable 5'-nucleotidase protein; Belongs to the 5'-nucleotidase family. | 0.909 |
| Meso_1622 | pncB | Meso_1622 | Meso_1739 | PFAM: CinA-like; KEGG: rpb:RPB_2886 CinA-like; Belongs to the CinA family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.934 |
| Meso_2725 | Meso_1611 | Meso_2725 | Meso_1611 | 5'-Nucleotidase-like protein; PFAM: Peptidoglycan-binding LysM metallophosphoesterase 5'-Nucleotidase-like; KEGG: ret:RHE_CH03555 probable 5'-nucleotidase protein; Belongs to the 5'-nucleotidase family. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: mlo:mll0404 MazG protein. | 0.915 |
| Meso_2725 | Meso_1622 | Meso_2725 | Meso_1622 | 5'-Nucleotidase-like protein; PFAM: Peptidoglycan-binding LysM metallophosphoesterase 5'-Nucleotidase-like; KEGG: ret:RHE_CH03555 probable 5'-nucleotidase protein; Belongs to the 5'-nucleotidase family. | PFAM: CinA-like; KEGG: rpb:RPB_2886 CinA-like; Belongs to the CinA family. | 0.909 |
| Meso_2725 | Meso_3479 | Meso_2725 | Meso_3479 | 5'-Nucleotidase-like protein; PFAM: Peptidoglycan-binding LysM metallophosphoesterase 5'-Nucleotidase-like; KEGG: ret:RHE_CH03555 probable 5'-nucleotidase protein; Belongs to the 5'-nucleotidase family. | Maf-like protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes 7- methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids; Belongs to the Maf family. YceF subfamily. | 0.902 |
| Meso_2725 | adk | Meso_2725 | Meso_1657 | 5'-Nucleotidase-like protein; PFAM: Peptidoglycan-binding LysM metallophosphoesterase 5'-Nucleotidase-like; KEGG: ret:RHE_CH03555 probable 5'-nucleotidase protein; Belongs to the 5'-nucleotidase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.907 |
| Meso_2725 | pncB | Meso_2725 | Meso_1739 | 5'-Nucleotidase-like protein; PFAM: Peptidoglycan-binding LysM metallophosphoesterase 5'-Nucleotidase-like; KEGG: ret:RHE_CH03555 probable 5'-nucleotidase protein; Belongs to the 5'-nucleotidase family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.916 |
| Meso_2725 | thyA | Meso_2725 | Meso_1751 | 5'-Nucleotidase-like protein; PFAM: Peptidoglycan-binding LysM metallophosphoesterase 5'-Nucleotidase-like; KEGG: ret:RHE_CH03555 probable 5'-nucleotidase protein; Belongs to the 5'-nucleotidase family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.916 |
