Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
Meso_1619Signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region, ATPase-like histidine kinase A-like PAS fold; SMART: PAS; KEGG: mlo:mlr0397 nitrogen reguration protein nirB protein. (377 aa)    
Predicted Functional Partners:
ntrC
Nitrogen metabolism transcriptional regulator, NtrC, Fis family; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
 0.998
Meso_1545
PFAM: nitrogen regulatory protein P-II; KEGG: ret:RHE_CH02103 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
  
 0.975
Meso_1620
tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
  
  
 0.896
Meso_1616
Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver sigma-54 factor, interaction region helix-turn-helix, Fis-type ATPase associated with various cellular activities, AAA_5; SMART: ATPase; KEGG: mlo:mlr0400 nitrogen assimilation regulatory protein NtrX.
 
 
 0.853
Meso_1740
Cell cycle control histidine kinase CckA; KEGG: mlo:mll0767 sensor kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver ATP-binding region, ATPase-like histidine kinase A-like PAS fold-4 PAS fold; SMART: PAS.
 
 
0.836
Meso_1942
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver GAF ATP-binding region, ATPase-like histidine kinase A-like; KEGG: ppu:PP3761 sensor histidine kinase/response regulator.
  
 
 0.826
Meso_3237
PFAM: nitrogen regulatory protein P-II; KEGG: atc:AGR_C_4999 probable nitrogen regulatory protein; Belongs to the P(II) protein family.
  
 
 0.767
Meso_3236
TIGRFAM: ammonium transporter; PFAM: Rh-like protein/ammonium transporter; KEGG: atc:AGR_C_5001 probable ammonium transporter protein; TC 1.A.11.
  
 
 0.762
Meso_2731
Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: response regulator receiver sigma-54 factor, interaction region helix-turn-helix, Fis-type ATPase associated with various cellular activities, AAA_5; SMART: ATPase; KEGG: mlo:mll3001 response regulatory protein.
 
 
 0.694
Meso_1617
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase-like histidine kinase, HAMP region histidine kinase A-like PAS fold; KEGG: mlo:mlr0399 nitrogen regulation protein ntrY.
 
   
0.685
Your Current Organism:
Chelativorans sp. BNC1
NCBI taxonomy Id: 266779
Other names: C. sp. BNC1, Mesorhizobium sp. BNC1
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