| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_1637 | Meso_1748 | Meso_1637 | Meso_1748 | KEGG: mlo:mlr0613 peptidyl-prolyl cis-trans isomerse D. | Protease FtsH subunit HflC; HflC and HflK could regulate a protease. | 0.597 |
| Meso_1637 | Meso_1749 | Meso_1637 | Meso_1749 | KEGG: mlo:mlr0613 peptidyl-prolyl cis-trans isomerse D. | Protease FtsH subunit HflK; HflC and HflK could encode or regulate a protease. | 0.485 |
| Meso_1747 | Meso_1748 | Meso_1747 | Meso_1748 | KEGG: bmb:BruAb1_1390 hypothetical protein. | Protease FtsH subunit HflC; HflC and HflK could regulate a protease. | 0.692 |
| Meso_1747 | Meso_1749 | Meso_1747 | Meso_1749 | KEGG: bmb:BruAb1_1390 hypothetical protein. | Protease FtsH subunit HflK; HflC and HflK could encode or regulate a protease. | 0.692 |
| Meso_1747 | Meso_1750 | Meso_1747 | Meso_1750 | KEGG: bmb:BruAb1_1390 hypothetical protein. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.505 |
| Meso_1747 | thyA | Meso_1747 | Meso_1751 | KEGG: bmb:BruAb1_1390 hypothetical protein. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.501 |
| Meso_1748 | Meso_1637 | Meso_1748 | Meso_1637 | Protease FtsH subunit HflC; HflC and HflK could regulate a protease. | KEGG: mlo:mlr0613 peptidyl-prolyl cis-trans isomerse D. | 0.597 |
| Meso_1748 | Meso_1747 | Meso_1748 | Meso_1747 | Protease FtsH subunit HflC; HflC and HflK could regulate a protease. | KEGG: bmb:BruAb1_1390 hypothetical protein. | 0.692 |
| Meso_1748 | Meso_1749 | Meso_1748 | Meso_1749 | Protease FtsH subunit HflC; HflC and HflK could regulate a protease. | Protease FtsH subunit HflK; HflC and HflK could encode or regulate a protease. | 0.993 |
| Meso_1748 | Meso_1750 | Meso_1748 | Meso_1750 | Protease FtsH subunit HflC; HflC and HflK could regulate a protease. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.571 |
| Meso_1748 | Meso_2428 | Meso_1748 | Meso_2428 | Protease FtsH subunit HflC; HflC and HflK could regulate a protease. | PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: sil:SPO0833 formate dehydrogenase, beta subunit. | 0.733 |
| Meso_1748 | Meso_2792 | Meso_1748 | Meso_2792 | Protease FtsH subunit HflC; HflC and HflK could regulate a protease. | PFAM: cytochrome c oxidase, subunit II cytochrome c, class I; KEGG: sme:SMb21368 putative cytochrome c oxidase chain II protein. | 0.759 |
| Meso_1748 | Meso_3348 | Meso_1748 | Meso_3348 | Protease FtsH subunit HflC; HflC and HflK could regulate a protease. | PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: mlo:mll4349 protein-tyrosine-phosphatase. | 0.577 |
| Meso_1748 | ftsH | Meso_1748 | Meso_3167 | Protease FtsH subunit HflC; HflC and HflK could regulate a protease. | Membrane protease FtsH catalytic subunit; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.893 |
| Meso_1748 | hflX | Meso_1748 | Meso_1612 | Protease FtsH subunit HflC; HflC and HflK could regulate a protease. | GTP-binding protein, HSR1-related protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.590 |
| Meso_1748 | thyA | Meso_1748 | Meso_1751 | Protease FtsH subunit HflC; HflC and HflK could regulate a protease. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.568 |
| Meso_1749 | Meso_1637 | Meso_1749 | Meso_1637 | Protease FtsH subunit HflK; HflC and HflK could encode or regulate a protease. | KEGG: mlo:mlr0613 peptidyl-prolyl cis-trans isomerse D. | 0.485 |
| Meso_1749 | Meso_1747 | Meso_1749 | Meso_1747 | Protease FtsH subunit HflK; HflC and HflK could encode or regulate a protease. | KEGG: bmb:BruAb1_1390 hypothetical protein. | 0.692 |
| Meso_1749 | Meso_1748 | Meso_1749 | Meso_1748 | Protease FtsH subunit HflK; HflC and HflK could encode or regulate a protease. | Protease FtsH subunit HflC; HflC and HflK could regulate a protease. | 0.993 |
| Meso_1749 | Meso_1750 | Meso_1749 | Meso_1750 | Protease FtsH subunit HflK; HflC and HflK could encode or regulate a protease. | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.571 |