node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Meso_0946 | Meso_2703 | Meso_0946 | Meso_2703 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.911 |
Meso_0946 | Meso_3256 | Meso_0946 | Meso_3256 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | PFAM: pyruvate kinase; KEGG: mlo:mll3819 pyruvate kinase; Belongs to the pyruvate kinase family. | 0.928 |
Meso_0946 | gmk | Meso_0946 | Meso_1763 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.930 |
Meso_0946 | guaA | Meso_0946 | Meso_0495 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.414 |
Meso_0946 | ndk | Meso_0946 | Meso_1979 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.921 |
Meso_1764 | gmk | Meso_1764 | Meso_1763 | TIGRFAM: conserved hypothetical protein; PFAM: YicC-like-like Domain of unknown function DUF1732; KEGG: mlo:mlr7856 hypothetical protein. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.925 |
Meso_2703 | Meso_0946 | Meso_2703 | Meso_0946 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.911 |
Meso_2703 | Meso_3256 | Meso_2703 | Meso_3256 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | PFAM: pyruvate kinase; KEGG: mlo:mll3819 pyruvate kinase; Belongs to the pyruvate kinase family. | 0.907 |
Meso_2703 | gmk | Meso_2703 | Meso_1763 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.932 |
Meso_2703 | guaA | Meso_2703 | Meso_0495 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.616 |
Meso_2703 | ndk | Meso_2703 | Meso_1979 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.939 |
Meso_3093 | Meso_3197 | Meso_3093 | Meso_3197 | TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: mlo:mll3520 hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | PFAM: glutamine amidotransferase class-I; KEGG: mlo:mll4216 glutamine amidotransferase. | 0.920 |
Meso_3093 | apt | Meso_3093 | Meso_2163 | TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: mlo:mll3520 hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.926 |
Meso_3093 | gmk | Meso_3093 | Meso_1763 | TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: mlo:mll3520 hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.944 |
Meso_3093 | gpt | Meso_3093 | Meso_1335 | TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: mlo:mll3520 hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.926 |
Meso_3093 | guaA | Meso_3093 | Meso_0495 | TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: mlo:mll3520 hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.952 |
Meso_3197 | Meso_3093 | Meso_3197 | Meso_3093 | PFAM: glutamine amidotransferase class-I; KEGG: mlo:mll4216 glutamine amidotransferase. | TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; KEGG: mlo:mll3520 hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.920 |
Meso_3197 | apt | Meso_3197 | Meso_2163 | PFAM: glutamine amidotransferase class-I; KEGG: mlo:mll4216 glutamine amidotransferase. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.927 |
Meso_3197 | gmk | Meso_3197 | Meso_1763 | PFAM: glutamine amidotransferase class-I; KEGG: mlo:mll4216 glutamine amidotransferase. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.920 |
Meso_3197 | gpt | Meso_3197 | Meso_1335 | PFAM: glutamine amidotransferase class-I; KEGG: mlo:mll4216 glutamine amidotransferase. | Phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.927 |