| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_0328 | Meso_0760 | Meso_0328 | Meso_0760 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: mlo:mll7517 threonine synthase. | 0.598 |
| Meso_0328 | Meso_1922 | Meso_0328 | Meso_1922 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: homoserine dehydrogenase amino acid-binding ACT homoserine dehydrogenase, NAD-binding; KEGG: mlo:mll0934 homoserine dehydrogenase. | 0.948 |
| Meso_0328 | Meso_3001 | Meso_0328 | Meso_3001 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: aspartate kinase aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase amino acid-binding ACT; KEGG: bmb:BruAb1_1850 aspartate kinase, monofunctional class; Belongs to the aspartokinase family. | 0.655 |
| Meso_0328 | asd | Meso_0328 | Meso_3384 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.610 |
| Meso_0328 | metAA | Meso_0328 | Meso_3083 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.864 |
| Meso_0328 | thrB | Meso_0328 | Meso_0749 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | TIGRFAM: homoserine kinase; PFAM: aminoglycoside phosphotransferase; KEGG: mlo:mlr7503 homoserine kinase; Belongs to the pseudomonas-type ThrB family. | 0.814 |
| Meso_0760 | Meso_0328 | Meso_0760 | Meso_0328 | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: mlo:mll7517 threonine synthase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.598 |
| Meso_0760 | Meso_1922 | Meso_0760 | Meso_1922 | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: mlo:mll7517 threonine synthase. | PFAM: homoserine dehydrogenase amino acid-binding ACT homoserine dehydrogenase, NAD-binding; KEGG: mlo:mll0934 homoserine dehydrogenase. | 0.925 |
| Meso_0760 | Meso_3001 | Meso_0760 | Meso_3001 | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: mlo:mll7517 threonine synthase. | TIGRFAM: aspartate kinase aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase amino acid-binding ACT; KEGG: bmb:BruAb1_1850 aspartate kinase, monofunctional class; Belongs to the aspartokinase family. | 0.822 |
| Meso_0760 | asd | Meso_0760 | Meso_3384 | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: mlo:mll7517 threonine synthase. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.555 |
| Meso_0760 | thrB | Meso_0760 | Meso_0749 | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: mlo:mll7517 threonine synthase. | TIGRFAM: homoserine kinase; PFAM: aminoglycoside phosphotransferase; KEGG: mlo:mlr7503 homoserine kinase; Belongs to the pseudomonas-type ThrB family. | 0.922 |
| Meso_1922 | Meso_0328 | Meso_1922 | Meso_0328 | PFAM: homoserine dehydrogenase amino acid-binding ACT homoserine dehydrogenase, NAD-binding; KEGG: mlo:mll0934 homoserine dehydrogenase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.948 |
| Meso_1922 | Meso_0760 | Meso_1922 | Meso_0760 | PFAM: homoserine dehydrogenase amino acid-binding ACT homoserine dehydrogenase, NAD-binding; KEGG: mlo:mll0934 homoserine dehydrogenase. | TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: mlo:mll7517 threonine synthase. | 0.925 |
| Meso_1922 | Meso_2416 | Meso_1922 | Meso_2416 | PFAM: homoserine dehydrogenase amino acid-binding ACT homoserine dehydrogenase, NAD-binding; KEGG: mlo:mll0934 homoserine dehydrogenase. | PFAM: aminotransferase class-III; KEGG: mlo:mll7127 putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.919 |
| Meso_1922 | Meso_3001 | Meso_1922 | Meso_3001 | PFAM: homoserine dehydrogenase amino acid-binding ACT homoserine dehydrogenase, NAD-binding; KEGG: mlo:mll0934 homoserine dehydrogenase. | TIGRFAM: aspartate kinase aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase amino acid-binding ACT; KEGG: bmb:BruAb1_1850 aspartate kinase, monofunctional class; Belongs to the aspartokinase family. | 0.969 |
| Meso_1922 | Meso_3139 | Meso_1922 | Meso_3139 | PFAM: homoserine dehydrogenase amino acid-binding ACT homoserine dehydrogenase, NAD-binding; KEGG: mlo:mll0934 homoserine dehydrogenase. | PFAM: dihydrodipicolinate synthetase; KEGG: rpa:RPA3190 possible dihydrodipicoline synthase related protein; Belongs to the DapA family. | 0.910 |
| Meso_1922 | Meso_3758 | Meso_1922 | Meso_3758 | PFAM: homoserine dehydrogenase amino acid-binding ACT homoserine dehydrogenase, NAD-binding; KEGG: mlo:mll0934 homoserine dehydrogenase. | PFAM: dihydrodipicolinate synthetase; KEGG: jan:Jann_3748 dihydrodipicolinate synthetase; Belongs to the DapA family. | 0.921 |
| Meso_1922 | asd | Meso_1922 | Meso_3384 | PFAM: homoserine dehydrogenase amino acid-binding ACT homoserine dehydrogenase, NAD-binding; KEGG: mlo:mll0934 homoserine dehydrogenase. | Aspartate semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.983 |
| Meso_1922 | dapA | Meso_1922 | Meso_0941 | PFAM: homoserine dehydrogenase amino acid-binding ACT homoserine dehydrogenase, NAD-binding; KEGG: mlo:mll0934 homoserine dehydrogenase. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.936 |
| Meso_1922 | metAA | Meso_1922 | Meso_3083 | PFAM: homoserine dehydrogenase amino acid-binding ACT homoserine dehydrogenase, NAD-binding; KEGG: mlo:mll0934 homoserine dehydrogenase. | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. | 0.947 |
