| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_0022 | Meso_0969 | Meso_0022 | Meso_0969 | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: mlo:mlr5628 probable acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase LeuA allosteric (dimerisation) domain; KEGG: mlo:mlr7805 homocitrate synthase nifV candidate; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.925 |
| Meso_0022 | Meso_1523 | Meso_0022 | Meso_1523 | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: mlo:mlr5628 probable acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: nwi:Nwi_2994 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.844 |
| Meso_0022 | Meso_1628 | Meso_0022 | Meso_1628 | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: mlo:mlr5628 probable acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.920 |
| Meso_0022 | Meso_1934 | Meso_0022 | Meso_1934 | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: mlo:mlr5628 probable acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | PFAM: CoA-binding; KEGG: eba:ebA5611 organic acid-CoA ligase (ADP forming),similar to feruloyl-CoA synthetase. | 0.908 |
| Meso_0022 | Meso_3374 | Meso_0022 | Meso_3374 | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: mlo:mlr5628 probable acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: mlo:mlr3847 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.831 |
| Meso_0022 | Meso_3505 | Meso_0022 | Meso_3505 | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: mlo:mlr5628 probable acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | PFAM: Thiolase; KEGG: sme:SMc00262 putative 3-ketoacyl-CoA thiolase protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.800 |
| Meso_0022 | acsA | Meso_0022 | Meso_3431 | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: mlo:mlr5628 probable acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.922 |
| Meso_0022 | glcB | Meso_0022 | Meso_3915 | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: mlo:mlr5628 probable acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.915 |
| Meso_0022 | leuA | Meso_0022 | Meso_2190 | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: mlo:mlr5628 probable acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.925 |
| Meso_0969 | Meso_0022 | Meso_0969 | Meso_0022 | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase LeuA allosteric (dimerisation) domain; KEGG: mlo:mlr7805 homocitrate synthase nifV candidate; Belongs to the alpha-IPM synthase/homocitrate synthase family. | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: mlo:mlr5628 probable acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.925 |
| Meso_0969 | Meso_1523 | Meso_0969 | Meso_1523 | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase LeuA allosteric (dimerisation) domain; KEGG: mlo:mlr7805 homocitrate synthase nifV candidate; Belongs to the alpha-IPM synthase/homocitrate synthase family. | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: nwi:Nwi_2994 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.925 |
| Meso_0969 | Meso_1628 | Meso_0969 | Meso_1628 | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase LeuA allosteric (dimerisation) domain; KEGG: mlo:mlr7805 homocitrate synthase nifV candidate; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.910 |
| Meso_0969 | Meso_1934 | Meso_0969 | Meso_1934 | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase LeuA allosteric (dimerisation) domain; KEGG: mlo:mlr7805 homocitrate synthase nifV candidate; Belongs to the alpha-IPM synthase/homocitrate synthase family. | PFAM: CoA-binding; KEGG: eba:ebA5611 organic acid-CoA ligase (ADP forming),similar to feruloyl-CoA synthetase. | 0.903 |
| Meso_0969 | Meso_3374 | Meso_0969 | Meso_3374 | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase LeuA allosteric (dimerisation) domain; KEGG: mlo:mlr7805 homocitrate synthase nifV candidate; Belongs to the alpha-IPM synthase/homocitrate synthase family. | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: mlo:mlr3847 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.925 |
| Meso_0969 | Meso_3505 | Meso_0969 | Meso_3505 | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase LeuA allosteric (dimerisation) domain; KEGG: mlo:mlr7805 homocitrate synthase nifV candidate; Belongs to the alpha-IPM synthase/homocitrate synthase family. | PFAM: Thiolase; KEGG: sme:SMc00262 putative 3-ketoacyl-CoA thiolase protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.925 |
| Meso_0969 | acsA | Meso_0969 | Meso_3431 | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase LeuA allosteric (dimerisation) domain; KEGG: mlo:mlr7805 homocitrate synthase nifV candidate; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.917 |
| Meso_0969 | glcB | Meso_0969 | Meso_3915 | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase LeuA allosteric (dimerisation) domain; KEGG: mlo:mlr7805 homocitrate synthase nifV candidate; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.903 |
| Meso_0969 | leuA | Meso_0969 | Meso_2190 | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase LeuA allosteric (dimerisation) domain; KEGG: mlo:mlr7805 homocitrate synthase nifV candidate; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.900 |
| Meso_1523 | Meso_0022 | Meso_1523 | Meso_0022 | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: nwi:Nwi_2994 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: mlo:mlr5628 probable acyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.844 |
| Meso_1523 | Meso_0969 | Meso_1523 | Meso_0969 | TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; KEGG: nwi:Nwi_2994 acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase LeuA allosteric (dimerisation) domain; KEGG: mlo:mlr7805 homocitrate synthase nifV candidate; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.925 |
