| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_2172 | Meso_2173 | Meso_2172 | Meso_2173 | Hypothetical protein. | PFAM: ABC transporter related; SMART: ATPase; KEGG: mlo:mll2715 ATP-binding protein of ABC transporter. | 0.737 |
| Meso_2172 | Meso_2174 | Meso_2172 | Meso_2174 | Hypothetical protein. | PFAM: ABC transporter related; SMART: ATPase; KEGG: sme:SMc00186 putative ABC transporter ATP-binding transmembrane protein. | 0.737 |
| Meso_2172 | trmL | Meso_2172 | Meso_2171 | Hypothetical protein. | tRNA/rRNA methyltransferase (SpoU); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.510 |
| Meso_2173 | Meso_2172 | Meso_2173 | Meso_2172 | PFAM: ABC transporter related; SMART: ATPase; KEGG: mlo:mll2715 ATP-binding protein of ABC transporter. | Hypothetical protein. | 0.737 |
| Meso_2173 | Meso_2174 | Meso_2173 | Meso_2174 | PFAM: ABC transporter related; SMART: ATPase; KEGG: mlo:mll2715 ATP-binding protein of ABC transporter. | PFAM: ABC transporter related; SMART: ATPase; KEGG: sme:SMc00186 putative ABC transporter ATP-binding transmembrane protein. | 0.984 |
| Meso_2173 | trmL | Meso_2173 | Meso_2171 | PFAM: ABC transporter related; SMART: ATPase; KEGG: mlo:mll2715 ATP-binding protein of ABC transporter. | tRNA/rRNA methyltransferase (SpoU); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.524 |
| Meso_2174 | Meso_2172 | Meso_2174 | Meso_2172 | PFAM: ABC transporter related; SMART: ATPase; KEGG: sme:SMc00186 putative ABC transporter ATP-binding transmembrane protein. | Hypothetical protein. | 0.737 |
| Meso_2174 | Meso_2173 | Meso_2174 | Meso_2173 | PFAM: ABC transporter related; SMART: ATPase; KEGG: sme:SMc00186 putative ABC transporter ATP-binding transmembrane protein. | PFAM: ABC transporter related; SMART: ATPase; KEGG: mlo:mll2715 ATP-binding protein of ABC transporter. | 0.984 |
| Meso_2174 | trmL | Meso_2174 | Meso_2171 | PFAM: ABC transporter related; SMART: ATPase; KEGG: sme:SMc00186 putative ABC transporter ATP-binding transmembrane protein. | tRNA/rRNA methyltransferase (SpoU); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.524 |
| Meso_3418 | rlmH | Meso_3418 | Meso_3453 | PFAM: Fmu (Sun) NusB/RsmB/TIM44; KEGG: mlo:mlr4098 hypothetical protein, similarity to RNA-binding Sun protein, putative Fmu protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.544 |
| Meso_3418 | rlmN | Meso_3418 | Meso_2859 | PFAM: Fmu (Sun) NusB/RsmB/TIM44; KEGG: mlo:mlr4098 hypothetical protein, similarity to RNA-binding Sun protein, putative Fmu protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.921 |
| Meso_3418 | trmB | Meso_3418 | Meso_3925 | PFAM: Fmu (Sun) NusB/RsmB/TIM44; KEGG: mlo:mlr4098 hypothetical protein, similarity to RNA-binding Sun protein, putative Fmu protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.785 |
| Meso_3418 | trmL | Meso_3418 | Meso_2171 | PFAM: Fmu (Sun) NusB/RsmB/TIM44; KEGG: mlo:mlr4098 hypothetical protein, similarity to RNA-binding Sun protein, putative Fmu protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA/rRNA methyltransferase (SpoU); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.444 |
| hemF | trmL | Meso_2169 | Meso_2171 | Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | tRNA/rRNA methyltransferase (SpoU); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.692 |
| nnrD | trmL | Meso_1546 | Meso_2171 | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | tRNA/rRNA methyltransferase (SpoU); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.447 |
| rlmH | Meso_3418 | Meso_3453 | Meso_3418 | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | PFAM: Fmu (Sun) NusB/RsmB/TIM44; KEGG: mlo:mlr4098 hypothetical protein, similarity to RNA-binding Sun protein, putative Fmu protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.544 |
| rlmH | rlmN | Meso_3453 | Meso_2859 | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.421 |
| rlmH | trmL | Meso_3453 | Meso_2171 | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | tRNA/rRNA methyltransferase (SpoU); Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. | 0.410 |
| rlmN | Meso_3418 | Meso_2859 | Meso_3418 | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | PFAM: Fmu (Sun) NusB/RsmB/TIM44; KEGG: mlo:mlr4098 hypothetical protein, similarity to RNA-binding Sun protein, putative Fmu protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.921 |
| rlmN | rlmH | Meso_2859 | Meso_3453 | 23S rRNA m(2)A-2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.421 |
