| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_0757 | Meso_1942 | Meso_0757 | Meso_1942 | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: bms:BR0481 sensory box/GGDEF domain/EAL domain protein; TIGRFAM: PAS sensor protein diguanylate cyclase; PFAM: conserved hypothetical protein EAL Diverse 7TM receptor, extracellular region 2 Diverse 7TM receptor, transmembrane region PAS fold-3; SMART: PAC motif. | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver GAF ATP-binding region, ATPase-like histidine kinase A-like; KEGG: ppu:PP3761 sensor histidine kinase/response regulator. | 0.961 |
| Meso_0757 | Meso_2220 | Meso_0757 | Meso_2220 | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: bms:BR0481 sensory box/GGDEF domain/EAL domain protein; TIGRFAM: PAS sensor protein diguanylate cyclase; PFAM: conserved hypothetical protein EAL Diverse 7TM receptor, extracellular region 2 Diverse 7TM receptor, transmembrane region PAS fold-3; SMART: PAC motif. | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding regulatory protein, Crp; KEGG: mlo:mll6578 nitrogen fixation regulation protein fixK. | 0.462 |
| Meso_0757 | Meso_2222 | Meso_0757 | Meso_2222 | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: bms:BR0481 sensory box/GGDEF domain/EAL domain protein; TIGRFAM: PAS sensor protein diguanylate cyclase; PFAM: conserved hypothetical protein EAL Diverse 7TM receptor, extracellular region 2 Diverse 7TM receptor, transmembrane region PAS fold-3; SMART: PAC motif. | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR response regulator receiver Sigma-70, region 4 type 2; KEGG: sme:SMa1227 FixJ transcriptional activator. | 0.476 |
| Meso_0757 | Meso_2223 | Meso_0757 | Meso_2223 | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: bms:BR0481 sensory box/GGDEF domain/EAL domain protein; TIGRFAM: PAS sensor protein diguanylate cyclase; PFAM: conserved hypothetical protein EAL Diverse 7TM receptor, extracellular region 2 Diverse 7TM receptor, transmembrane region PAS fold-3; SMART: PAC motif. | Multi-sensor signal transduction histidine kinase; KEGG: sme:SMa1229 FixL oxygen regulated histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase-like histidine kinase A-like PAS fold-4 PAS fold; SMART: PAS. | 0.694 |
| Meso_1942 | Meso_0757 | Meso_1942 | Meso_0757 | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver GAF ATP-binding region, ATPase-like histidine kinase A-like; KEGG: ppu:PP3761 sensor histidine kinase/response regulator. | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: bms:BR0481 sensory box/GGDEF domain/EAL domain protein; TIGRFAM: PAS sensor protein diguanylate cyclase; PFAM: conserved hypothetical protein EAL Diverse 7TM receptor, extracellular region 2 Diverse 7TM receptor, transmembrane region PAS fold-3; SMART: PAC motif. | 0.961 |
| Meso_1942 | Meso_2220 | Meso_1942 | Meso_2220 | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver GAF ATP-binding region, ATPase-like histidine kinase A-like; KEGG: ppu:PP3761 sensor histidine kinase/response regulator. | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding regulatory protein, Crp; KEGG: mlo:mll6578 nitrogen fixation regulation protein fixK. | 0.563 |
| Meso_1942 | Meso_2222 | Meso_1942 | Meso_2222 | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver GAF ATP-binding region, ATPase-like histidine kinase A-like; KEGG: ppu:PP3761 sensor histidine kinase/response regulator. | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR response regulator receiver Sigma-70, region 4 type 2; KEGG: sme:SMa1227 FixJ transcriptional activator. | 0.633 |
| Meso_1942 | Meso_2223 | Meso_1942 | Meso_2223 | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver GAF ATP-binding region, ATPase-like histidine kinase A-like; KEGG: ppu:PP3761 sensor histidine kinase/response regulator. | Multi-sensor signal transduction histidine kinase; KEGG: sme:SMa1229 FixL oxygen regulated histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase-like histidine kinase A-like PAS fold-4 PAS fold; SMART: PAS. | 0.938 |
| Meso_1942 | guaB | Meso_1942 | Meso_0467 | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver GAF ATP-binding region, ATPase-like histidine kinase A-like; KEGG: ppu:PP3761 sensor histidine kinase/response regulator. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.476 |
| Meso_1942 | rpoB | Meso_1942 | Meso_1819 | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver GAF ATP-binding region, ATPase-like histidine kinase A-like; KEGG: ppu:PP3761 sensor histidine kinase/response regulator. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.442 |
| Meso_1942 | rpoC | Meso_1942 | Meso_1818 | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver GAF ATP-binding region, ATPase-like histidine kinase A-like; KEGG: ppu:PP3761 sensor histidine kinase/response regulator. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.424 |
| Meso_1942 | rpoZ | Meso_1942 | Meso_0945 | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver GAF ATP-binding region, ATPase-like histidine kinase A-like; KEGG: ppu:PP3761 sensor histidine kinase/response regulator. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.453 |
| Meso_2220 | Meso_0757 | Meso_2220 | Meso_0757 | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding regulatory protein, Crp; KEGG: mlo:mll6578 nitrogen fixation regulation protein fixK. | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: bms:BR0481 sensory box/GGDEF domain/EAL domain protein; TIGRFAM: PAS sensor protein diguanylate cyclase; PFAM: conserved hypothetical protein EAL Diverse 7TM receptor, extracellular region 2 Diverse 7TM receptor, transmembrane region PAS fold-3; SMART: PAC motif. | 0.462 |
| Meso_2220 | Meso_1942 | Meso_2220 | Meso_1942 | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding regulatory protein, Crp; KEGG: mlo:mll6578 nitrogen fixation regulation protein fixK. | Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver GAF ATP-binding region, ATPase-like histidine kinase A-like; KEGG: ppu:PP3761 sensor histidine kinase/response regulator. | 0.563 |
| Meso_2220 | Meso_2221 | Meso_2220 | Meso_2221 | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding regulatory protein, Crp; KEGG: mlo:mll6578 nitrogen fixation regulation protein fixK. | KEGG: nwi:Nwi_1027 response regulator receiver. | 0.559 |
| Meso_2220 | Meso_2222 | Meso_2220 | Meso_2222 | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding regulatory protein, Crp; KEGG: mlo:mll6578 nitrogen fixation regulation protein fixK. | Two component transcriptional regulator, LuxR family; PFAM: regulatory protein, LuxR response regulator receiver Sigma-70, region 4 type 2; KEGG: sme:SMa1227 FixJ transcriptional activator. | 0.600 |
| Meso_2220 | Meso_2223 | Meso_2220 | Meso_2223 | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding regulatory protein, Crp; KEGG: mlo:mll6578 nitrogen fixation regulation protein fixK. | Multi-sensor signal transduction histidine kinase; KEGG: sme:SMa1229 FixL oxygen regulated histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region, ATPase-like histidine kinase A-like PAS fold-4 PAS fold; SMART: PAS. | 0.706 |
| Meso_2220 | guaB | Meso_2220 | Meso_0467 | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding regulatory protein, Crp; KEGG: mlo:mll6578 nitrogen fixation regulation protein fixK. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.498 |
| Meso_2220 | rpoA | Meso_2220 | Meso_1654 | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding regulatory protein, Crp; KEGG: mlo:mll6578 nitrogen fixation regulation protein fixK. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.649 |
| Meso_2220 | rpoB | Meso_2220 | Meso_1819 | Transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding regulatory protein, Crp; KEGG: mlo:mll6578 nitrogen fixation regulation protein fixK. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.665 |
