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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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filled nodes:
a 3D structure is known or predicted
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[Homology]
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thiGThiazole-phosphate synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (258 aa)    
Predicted Functional Partners:
Meso_2563
TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS; KEGG: mlo:msl5792 thiamin biosynthesis ThiS.
 
 
 0.998
Meso_2562
TIGRFAM: glycine oxidase ThiO; PFAM: FAD dependent oxidoreductase; KEGG: mlo:mll5793 thiamine biosynthesis oxidoreductase ThiO.
 
 0.997
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
 0.997
Meso_2566
TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: mlo:mll5788 phosphomethylpyrimidine kinase.
 
  
 0.988
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
 
  
 0.960
Meso_0004
PFAM: UBA/THIF-type NAD/FAD binding fold MoeZ/MoeB; KEGG: mlo:mll5577 molybdenum cofactor biosynthesis protein.
 
  
 0.929
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
     
 0.927
Meso_3182
PFAM: thiamine monophosphate synthase; KEGG: mlo:mlr3913 thiamine-phosphate pyrophosphorylase.
  
  
 0.800
Meso_1839
PFAM: FAD dependent oxidoreductase; KEGG: bbr:BB0994 probable FAD dependent oxidoreductase.
 
  
 0.717
panB
Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
  
 0.477
Your Current Organism:
Chelativorans sp. BNC1
NCBI taxonomy Id: 266779
Other names: C. sp. BNC1, Mesorhizobium sp. BNC1
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