Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hutHTIGRFAM: histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase; KEGG: ret:RHE_PE00072 histidine ammonia-lyase protein; Belongs to the PAL/histidase family. (511 aa)    
Predicted Functional Partners:
hutU-2
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 0.998
Meso_2545
TIGRFAM: urocanate hydratase; PFAM: Urocanase; KEGG: sth:STH3193 urocanase.
 
 0.991
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 0.991
hutI
TIGRFAM: imidazolonepropionase; PFAM: amidohydrolase Amidohydrolase 3; KEGG: ret:RHE_PE00073 imidazolonepropionase protein; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
  
 0.983
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
    
 0.908
Meso_2984
PFAM: N-formylglutamate amidohydrolase; KEGG: ret:RHE_PE00071 formiminoglutamase protein.
 
  
 0.896
Meso_2987
TIGRFAM: formiminoglutamate deiminase; PFAM: amidohydrolase; KEGG: ret:RHE_PE00074 probable cytosine deaminase protein.
 
  
 0.811
Meso_2982
PFAM: protein of unknown function DUF886; KEGG: ret:RHE_PE00069 hypothetical protein.
  
  
 0.781
Meso_2988
Transcriptional regulator, histidine utilization repressor, GntR family; TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR, HTH UbiC transcription regulator-associated; KEGG: ret:RHE_PE00075 probable transcriptional regulator protein, GntR family.
 
  
 0.745
Meso_3137
PFAM: amidohydrolase Amidohydrolase 3; KEGG: bja:bll5494 hypothetical protein.
  
  
 0.648
Your Current Organism:
Chelativorans sp. BNC1
NCBI taxonomy Id: 266779
Other names: C. sp. BNC1, Mesorhizobium sp. BNC1
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.