| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_0918 | Meso_1629 | Meso_0918 | Meso_1629 | 3-methylcrotonoyl-CoA carboxylase, alpha subunit; PFAM: biotin/lipoyl attachment ATP-dependent carboxylate-amine ligase-like, ATP-grasp Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll7727 3-methylcrotonyl-CoA carboxylase biotin-containing subunit. | Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.981 |
| Meso_0918 | Meso_1715 | Meso_0918 | Meso_1715 | 3-methylcrotonoyl-CoA carboxylase, alpha subunit; PFAM: biotin/lipoyl attachment ATP-dependent carboxylate-amine ligase-like, ATP-grasp Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll7727 3-methylcrotonyl-CoA carboxylase biotin-containing subunit. | Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.953 |
| Meso_0918 | Meso_1769 | Meso_0918 | Meso_1769 | 3-methylcrotonoyl-CoA carboxylase, alpha subunit; PFAM: biotin/lipoyl attachment ATP-dependent carboxylate-amine ligase-like, ATP-grasp Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll7727 3-methylcrotonyl-CoA carboxylase biotin-containing subunit. | [Acyl-carrier-protein] S-malonyltransferase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase region; KEGG: mlo:mlr7849 malonyl CoA-acyl carrier protein transacylase. | 0.721 |
| Meso_0918 | accA | Meso_0918 | Meso_3061 | 3-methylcrotonoyl-CoA carboxylase, alpha subunit; PFAM: biotin/lipoyl attachment ATP-dependent carboxylate-amine ligase-like, ATP-grasp Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll7727 3-methylcrotonyl-CoA carboxylase biotin-containing subunit. | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 0.976 |
| Meso_0918 | accD | Meso_0918 | Meso_0663 | 3-methylcrotonoyl-CoA carboxylase, alpha subunit; PFAM: biotin/lipoyl attachment ATP-dependent carboxylate-amine ligase-like, ATP-grasp Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll7727 3-methylcrotonyl-CoA carboxylase biotin-containing subunit. | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. | 0.981 |
| Meso_0918 | fabH | Meso_0918 | Meso_1146 | 3-methylcrotonoyl-CoA carboxylase, alpha subunit; PFAM: biotin/lipoyl attachment ATP-dependent carboxylate-amine ligase-like, ATP-grasp Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll7727 3-methylcrotonyl-CoA carboxylase biotin-containing subunit. | 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.558 |
| Meso_0918 | fabZ | Meso_0918 | Meso_1390 | 3-methylcrotonoyl-CoA carboxylase, alpha subunit; PFAM: biotin/lipoyl attachment ATP-dependent carboxylate-amine ligase-like, ATP-grasp Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll7727 3-methylcrotonyl-CoA carboxylase biotin-containing subunit. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.693 |
| Meso_1020 | Meso_1629 | Meso_1020 | Meso_1629 | Biotin carboxyl carrier protein / biotin carboxylase; PFAM: biotin/lipoyl attachment Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll0871 propionyl-CoA carboxylase alpha chain precursor. | Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.981 |
| Meso_1020 | Meso_1715 | Meso_1020 | Meso_1715 | Biotin carboxyl carrier protein / biotin carboxylase; PFAM: biotin/lipoyl attachment Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll0871 propionyl-CoA carboxylase alpha chain precursor. | Biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.947 |
| Meso_1020 | Meso_1769 | Meso_1020 | Meso_1769 | Biotin carboxyl carrier protein / biotin carboxylase; PFAM: biotin/lipoyl attachment Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll0871 propionyl-CoA carboxylase alpha chain precursor. | [Acyl-carrier-protein] S-malonyltransferase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase region; KEGG: mlo:mlr7849 malonyl CoA-acyl carrier protein transacylase. | 0.730 |
| Meso_1020 | accA | Meso_1020 | Meso_3061 | Biotin carboxyl carrier protein / biotin carboxylase; PFAM: biotin/lipoyl attachment Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll0871 propionyl-CoA carboxylase alpha chain precursor. | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 0.973 |
| Meso_1020 | accD | Meso_1020 | Meso_0663 | Biotin carboxyl carrier protein / biotin carboxylase; PFAM: biotin/lipoyl attachment Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll0871 propionyl-CoA carboxylase alpha chain precursor. | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. | 0.979 |
| Meso_1020 | acsA | Meso_1020 | Meso_3431 | Biotin carboxyl carrier protein / biotin carboxylase; PFAM: biotin/lipoyl attachment Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll0871 propionyl-CoA carboxylase alpha chain precursor. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.918 |
| Meso_1020 | fabH | Meso_1020 | Meso_1146 | Biotin carboxyl carrier protein / biotin carboxylase; PFAM: biotin/lipoyl attachment Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll0871 propionyl-CoA carboxylase alpha chain precursor. | 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.538 |
| Meso_1020 | fabZ | Meso_1020 | Meso_1390 | Biotin carboxyl carrier protein / biotin carboxylase; PFAM: biotin/lipoyl attachment Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll0871 propionyl-CoA carboxylase alpha chain precursor. | 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.682 |
| Meso_1629 | Meso_0918 | Meso_1629 | Meso_0918 | Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 3-methylcrotonoyl-CoA carboxylase, alpha subunit; PFAM: biotin/lipoyl attachment ATP-dependent carboxylate-amine ligase-like, ATP-grasp Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll7727 3-methylcrotonyl-CoA carboxylase biotin-containing subunit. | 0.981 |
| Meso_1629 | Meso_1020 | Meso_1629 | Meso_1020 | Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Biotin carboxyl carrier protein / biotin carboxylase; PFAM: biotin/lipoyl attachment Carbamoyl-phosphate synthase L chain, ATP-binding Carbamoyl-phosphate synthetase large chain-like biotin carboxylase-like RimK-like ATP-grasp; KEGG: mlo:mll0871 propionyl-CoA carboxylase alpha chain precursor. | 0.981 |
| Meso_1629 | Meso_1716 | Meso_1629 | Meso_1716 | Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | acetyl-CoA carboxylase carboxyltransferase subunit alpha; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.977 |
| Meso_1629 | Meso_1769 | Meso_1629 | Meso_1769 | Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | [Acyl-carrier-protein] S-malonyltransferase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase region; KEGG: mlo:mlr7849 malonyl CoA-acyl carrier protein transacylase. | 0.698 |
| Meso_1629 | accA | Meso_1629 | Meso_3061 | Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | acetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 0.968 |