| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_0675 | pheS | Meso_0675 | Meso_0676 | Mn2+-dependent serine/threonine protein kinase; KEGG: bmb:BruAb1_2096 hypothetical protein. | TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase, class IIc aminoacyl tRNA synthetase, class II-like; KEGG: mlo:mll5055 phenylalanyl-tRNA synthetase, alpha-subunit; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.801 |
| Meso_0675 | tsaD | Meso_0675 | Meso_3203 | Mn2+-dependent serine/threonine protein kinase; KEGG: bmb:BruAb1_2096 hypothetical protein. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.949 |
| Meso_0715 | Meso_3578 | Meso_0715 | Meso_3578 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | PFAM: aminoglycoside phosphotransferase protein of unknown function UPF0079; KEGG: mlo:mll5086 hypothetical protein. | 0.402 |
| Meso_0715 | tsaD | Meso_0715 | Meso_3203 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.709 |
| Meso_3201 | Meso_3205 | Meso_3201 | Meso_3205 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | PFAM: YCII-related; KEGG: ret:RHE_CH03901 hypothetical protein. | 0.500 |
| Meso_3201 | Meso_3206 | Meso_3201 | Meso_3206 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | PFAM: protein of unknown function DUF55; KEGG: bhe:BH16120 hypothetical protein. | 0.561 |
| Meso_3201 | gpsA | Meso_3201 | Meso_3204 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | PFAM: UBA/THIF-type NAD/FAD binding fold NADP oxidoreductase, coenzyme F420-dependent NAD-dependent glycerol-3-phosphate dehydrogenase-like Ketopantoate reductase ApbA/PanE-like; KEGG: mlo:mlr4225 glycerol-3-phosphate dehydrogenase. | 0.609 |
| Meso_3201 | hemC | Meso_3201 | Meso_3202 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.997 |
| Meso_3201 | tsaD | Meso_3201 | Meso_3203 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.680 |
| Meso_3205 | Meso_3201 | Meso_3205 | Meso_3201 | PFAM: YCII-related; KEGG: ret:RHE_CH03901 hypothetical protein. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.500 |
| Meso_3205 | Meso_3206 | Meso_3205 | Meso_3206 | PFAM: YCII-related; KEGG: ret:RHE_CH03901 hypothetical protein. | PFAM: protein of unknown function DUF55; KEGG: bhe:BH16120 hypothetical protein. | 0.827 |
| Meso_3205 | gpsA | Meso_3205 | Meso_3204 | PFAM: YCII-related; KEGG: ret:RHE_CH03901 hypothetical protein. | PFAM: UBA/THIF-type NAD/FAD binding fold NADP oxidoreductase, coenzyme F420-dependent NAD-dependent glycerol-3-phosphate dehydrogenase-like Ketopantoate reductase ApbA/PanE-like; KEGG: mlo:mlr4225 glycerol-3-phosphate dehydrogenase. | 0.634 |
| Meso_3205 | hemC | Meso_3205 | Meso_3202 | PFAM: YCII-related; KEGG: ret:RHE_CH03901 hypothetical protein. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.505 |
| Meso_3205 | tsaD | Meso_3205 | Meso_3203 | PFAM: YCII-related; KEGG: ret:RHE_CH03901 hypothetical protein. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.634 |
| Meso_3206 | Meso_3201 | Meso_3206 | Meso_3201 | PFAM: protein of unknown function DUF55; KEGG: bhe:BH16120 hypothetical protein. | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.561 |
| Meso_3206 | Meso_3205 | Meso_3206 | Meso_3205 | PFAM: protein of unknown function DUF55; KEGG: bhe:BH16120 hypothetical protein. | PFAM: YCII-related; KEGG: ret:RHE_CH03901 hypothetical protein. | 0.827 |
| Meso_3206 | gpsA | Meso_3206 | Meso_3204 | PFAM: protein of unknown function DUF55; KEGG: bhe:BH16120 hypothetical protein. | PFAM: UBA/THIF-type NAD/FAD binding fold NADP oxidoreductase, coenzyme F420-dependent NAD-dependent glycerol-3-phosphate dehydrogenase-like Ketopantoate reductase ApbA/PanE-like; KEGG: mlo:mlr4225 glycerol-3-phosphate dehydrogenase. | 0.634 |
| Meso_3206 | hemC | Meso_3206 | Meso_3202 | PFAM: protein of unknown function DUF55; KEGG: bhe:BH16120 hypothetical protein. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.500 |
| Meso_3206 | tsaD | Meso_3206 | Meso_3203 | PFAM: protein of unknown function DUF55; KEGG: bhe:BH16120 hypothetical protein. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.673 |
| Meso_3578 | Meso_0715 | Meso_3578 | Meso_0715 | PFAM: aminoglycoside phosphotransferase protein of unknown function UPF0079; KEGG: mlo:mll5086 hypothetical protein. | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.402 |