| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_0056 | Meso_0482 | Meso_0056 | Meso_0482 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like FAD dependent oxidoreductase; KEGG: gme:Gmet_1533 fumarate reductase/succinate dehydrogenase flavoprotein-like. | 0.852 |
| Meso_0056 | Meso_1064 | Meso_0056 | Meso_1064 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like FAD dependent oxidoreductase; KEGG: bcl:ABC0629 hypothetical protein. | 0.852 |
| Meso_0056 | Meso_2428 | Meso_0056 | Meso_2428 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: sil:SPO0833 formate dehydrogenase, beta subunit. | 0.856 |
| Meso_0056 | Meso_3243 | Meso_0056 | Meso_3243 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: mlo:mll4260 succinate dehydrogenase iron-sulfur protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.990 |
| Meso_0056 | Meso_3244 | Meso_0056 | Meso_3244 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | TIGRFAM: succinate dehydrogenase, flavoprotein subunit succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like FAD dependent oxidoreductase; KEGG: bme:BMEI0161 succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.984 |
| Meso_0056 | Meso_3245 | Meso_0056 | Meso_3245 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: bms:BR1903 succinate dehydrogenase, hydrophobic membrane anchor protein, putative. | 0.982 |
| Meso_0056 | Meso_3246 | Meso_0056 | Meso_3246 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: mlo:mll4266 succinate dehydrogenase membrane anchor subunit. | 0.982 |
| Meso_0056 | sucC | Meso_0056 | Meso_3396 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.727 |
| Meso_0056 | sucD | Meso_0056 | Meso_3397 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.633 |
| Meso_0482 | Meso_0056 | Meso_0482 | Meso_0056 | PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like FAD dependent oxidoreductase; KEGG: gme:Gmet_1533 fumarate reductase/succinate dehydrogenase flavoprotein-like. | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.852 |
| Meso_0482 | Meso_2428 | Meso_0482 | Meso_2428 | PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like FAD dependent oxidoreductase; KEGG: gme:Gmet_1533 fumarate reductase/succinate dehydrogenase flavoprotein-like. | PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: sil:SPO0833 formate dehydrogenase, beta subunit. | 0.968 |
| Meso_0482 | Meso_2792 | Meso_0482 | Meso_2792 | PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like FAD dependent oxidoreductase; KEGG: gme:Gmet_1533 fumarate reductase/succinate dehydrogenase flavoprotein-like. | PFAM: cytochrome c oxidase, subunit II cytochrome c, class I; KEGG: sme:SMb21368 putative cytochrome c oxidase chain II protein. | 0.779 |
| Meso_0482 | Meso_3243 | Meso_0482 | Meso_3243 | PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like FAD dependent oxidoreductase; KEGG: gme:Gmet_1533 fumarate reductase/succinate dehydrogenase flavoprotein-like. | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: mlo:mll4260 succinate dehydrogenase iron-sulfur protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.967 |
| Meso_0482 | Meso_3245 | Meso_0482 | Meso_3245 | PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like FAD dependent oxidoreductase; KEGG: gme:Gmet_1533 fumarate reductase/succinate dehydrogenase flavoprotein-like. | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: bms:BR1903 succinate dehydrogenase, hydrophobic membrane anchor protein, putative. | 0.927 |
| Meso_0482 | Meso_3246 | Meso_0482 | Meso_3246 | PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like FAD dependent oxidoreductase; KEGG: gme:Gmet_1533 fumarate reductase/succinate dehydrogenase flavoprotein-like. | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: mlo:mll4266 succinate dehydrogenase membrane anchor subunit. | 0.946 |
| Meso_0482 | sucC | Meso_0482 | Meso_3396 | PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like FAD dependent oxidoreductase; KEGG: gme:Gmet_1533 fumarate reductase/succinate dehydrogenase flavoprotein-like. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.790 |
| Meso_0482 | sucD | Meso_0482 | Meso_3397 | PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like FAD dependent oxidoreductase; KEGG: gme:Gmet_1533 fumarate reductase/succinate dehydrogenase flavoprotein-like. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.783 |
| Meso_1064 | Meso_0056 | Meso_1064 | Meso_0056 | PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like FAD dependent oxidoreductase; KEGG: bcl:ABC0629 hypothetical protein. | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.852 |
| Meso_1064 | Meso_2428 | Meso_1064 | Meso_2428 | PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like FAD dependent oxidoreductase; KEGG: bcl:ABC0629 hypothetical protein. | PFAM: Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: sil:SPO0833 formate dehydrogenase, beta subunit. | 0.968 |
| Meso_1064 | Meso_2792 | Meso_1064 | Meso_2792 | PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like FAD dependent oxidoreductase; KEGG: bcl:ABC0629 hypothetical protein. | PFAM: cytochrome c oxidase, subunit II cytochrome c, class I; KEGG: sme:SMb21368 putative cytochrome c oxidase chain II protein. | 0.779 |