| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_0856 | Meso_1628 | Meso_0856 | Meso_1628 | TIGRFAM: methylmalonyl-CoA mutase, large subunit Methylmalonyl-CoA mutase-like; PFAM: methylmalonyl-CoA mutase cobalamin B12-binding; KEGG: mlo:mll7619 methylmalonyl-CoA large subunit. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.822 |
| Meso_0856 | Meso_3243 | Meso_0856 | Meso_3243 | TIGRFAM: methylmalonyl-CoA mutase, large subunit Methylmalonyl-CoA mutase-like; PFAM: methylmalonyl-CoA mutase cobalamin B12-binding; KEGG: mlo:mll7619 methylmalonyl-CoA large subunit. | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: mlo:mll4260 succinate dehydrogenase iron-sulfur protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.412 |
| Meso_0856 | Meso_3399 | Meso_0856 | Meso_3399 | TIGRFAM: methylmalonyl-CoA mutase, large subunit Methylmalonyl-CoA mutase-like; PFAM: methylmalonyl-CoA mutase cobalamin B12-binding; KEGG: mlo:mll7619 methylmalonyl-CoA large subunit. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.822 |
| Meso_0856 | mdh | Meso_0856 | Meso_3395 | TIGRFAM: methylmalonyl-CoA mutase, large subunit Methylmalonyl-CoA mutase-like; PFAM: methylmalonyl-CoA mutase cobalamin B12-binding; KEGG: mlo:mll7619 methylmalonyl-CoA large subunit. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.877 |
| Meso_0856 | sucC | Meso_0856 | Meso_3396 | TIGRFAM: methylmalonyl-CoA mutase, large subunit Methylmalonyl-CoA mutase-like; PFAM: methylmalonyl-CoA mutase cobalamin B12-binding; KEGG: mlo:mll7619 methylmalonyl-CoA large subunit. | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.942 |
| Meso_0856 | sucD | Meso_0856 | Meso_3397 | TIGRFAM: methylmalonyl-CoA mutase, large subunit Methylmalonyl-CoA mutase-like; PFAM: methylmalonyl-CoA mutase cobalamin B12-binding; KEGG: mlo:mll7619 methylmalonyl-CoA large subunit. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.952 |
| Meso_1628 | Meso_0856 | Meso_1628 | Meso_0856 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | TIGRFAM: methylmalonyl-CoA mutase, large subunit Methylmalonyl-CoA mutase-like; PFAM: methylmalonyl-CoA mutase cobalamin B12-binding; KEGG: mlo:mll7619 methylmalonyl-CoA large subunit. | 0.822 |
| Meso_1628 | Meso_3243 | Meso_1628 | Meso_3243 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: mlo:mll4260 succinate dehydrogenase iron-sulfur protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.715 |
| Meso_1628 | Meso_3244 | Meso_1628 | Meso_3244 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | TIGRFAM: succinate dehydrogenase, flavoprotein subunit succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like FAD dependent oxidoreductase; KEGG: bme:BMEI0161 succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.639 |
| Meso_1628 | Meso_3246 | Meso_1628 | Meso_3246 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: mlo:mll4266 succinate dehydrogenase membrane anchor subunit. | 0.454 |
| Meso_1628 | Meso_3398 | Meso_1628 | Meso_3398 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component Transketolase, central region; KEGG: mlo:mll4301 alpha-ketoglutarate dehydrogenase. | 0.994 |
| Meso_1628 | Meso_3399 | Meso_1628 | Meso_3399 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.888 |
| Meso_1628 | mdh | Meso_1628 | Meso_3395 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.518 |
| Meso_1628 | sucC | Meso_1628 | Meso_3396 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.992 |
| Meso_1628 | sucD | Meso_1628 | Meso_3397 | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.989 |
| Meso_3243 | Meso_0856 | Meso_3243 | Meso_0856 | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: mlo:mll4260 succinate dehydrogenase iron-sulfur protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | TIGRFAM: methylmalonyl-CoA mutase, large subunit Methylmalonyl-CoA mutase-like; PFAM: methylmalonyl-CoA mutase cobalamin B12-binding; KEGG: mlo:mll7619 methylmalonyl-CoA large subunit. | 0.412 |
| Meso_3243 | Meso_1628 | Meso_3243 | Meso_1628 | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: mlo:mll4260 succinate dehydrogenase iron-sulfur protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.715 |
| Meso_3243 | Meso_3244 | Meso_3243 | Meso_3244 | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: mlo:mll4260 succinate dehydrogenase iron-sulfur protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | TIGRFAM: succinate dehydrogenase, flavoprotein subunit succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein-like FAD dependent oxidoreductase; KEGG: bme:BMEI0161 succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.999 |
| Meso_3243 | Meso_3245 | Meso_3243 | Meso_3245 | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: mlo:mll4260 succinate dehydrogenase iron-sulfur protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: bms:BR1903 succinate dehydrogenase, hydrophobic membrane anchor protein, putative. | 0.999 |
| Meso_3243 | Meso_3246 | Meso_3243 | Meso_3246 | TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: mlo:mll4260 succinate dehydrogenase iron-sulfur protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: mlo:mll4266 succinate dehydrogenase membrane anchor subunit. | 0.999 |