Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (388 aa)    
Predicted Functional Partners:
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: sme:SMc02163 probable glucose-6-phosphate isomerase protein.
  
 0.980
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
  
 0.939
Meso_3440
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.932
Meso_0989
TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX; KEGG: bmb:BruAb1_1274 GlpX protein.
   
 
 0.928
Meso_0456
Mannose-6-phosphate isomerase, type 2; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase, type II Nucleotidyl transferase Cupin 2, conserved barrel; KEGG: bms:BRA0347 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase.
    
 0.927
Meso_3436
PFAM: fructose-bisphosphate aldolase, class-I; KEGG: atc:AGR_L_2190 putative fructose bisphosphate aldolase.
  
 0.926
Meso_0836
PfkB; PFAM: PfkB; KEGG: rsp:RSP_2257 putative fructokinase; Belongs to the carbohydrate kinase PfkB family.
  
 0.921
Meso_3617
PFAM: Transketolase-like; KEGG: mlo:mll5765 transketolase.
    
 0.906
Meso_3618
Transketolase subunit B; PFAM: Transketolase, central region Transketolase-like; KEGG: psp:PSPPH_1255 transketolase, C-terminal subunit, putative.
    
  0.903
Meso_3256
PFAM: pyruvate kinase; KEGG: mlo:mll3819 pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.891
Your Current Organism:
Chelativorans sp. BNC1
NCBI taxonomy Id: 266779
Other names: C. sp. BNC1, Mesorhizobium sp. BNC1
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