| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_3489 | Meso_3491 | Meso_3489 | Meso_3491 | KEGG: mlo:mll5001 hypothetical protein. | PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc02576 hypothetical acetyltransferase protein. | 0.649 |
| Meso_3489 | Meso_3494 | Meso_3489 | Meso_3494 | KEGG: mlo:mll5001 hypothetical protein. | KEGG: mlo:mlr5010 hypothetical protein. | 0.519 |
| Meso_3489 | coaA | Meso_3489 | Meso_3499 | KEGG: mlo:mll5001 hypothetical protein. | TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: mlo:mlr5019 pantothenate kinase. | 0.412 |
| Meso_3489 | hisA | Meso_3489 | Meso_3496 | KEGG: mlo:mll5001 hypothetical protein. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis; KEGG: sme:SMc02570 probable phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase protein. | 0.411 |
| Meso_3489 | hisB | Meso_3489 | Meso_3493 | KEGG: mlo:mll5001 hypothetical protein. | PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: mlo:mlr5008 imidazoleglycerol-phosphate dehydratase. | 0.451 |
| Meso_3489 | hisE | Meso_3489 | Meso_3498 | KEGG: mlo:mll5001 hypothetical protein. | PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mlo:mlr5018 phosphoribosyl-ATP pyrophosphatase. | 0.441 |
| Meso_3489 | hisF | Meso_3489 | Meso_3497 | KEGG: mlo:mll5001 hypothetical protein. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.410 |
| Meso_3489 | hisH | Meso_3489 | Meso_3495 | KEGG: mlo:mll5001 hypothetical protein. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.441 |
| Meso_3489 | hslU | Meso_3489 | Meso_3490 | KEGG: mlo:mll5001 hypothetical protein. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.648 |
| Meso_3489 | hslV | Meso_3489 | Meso_3492 | KEGG: mlo:mll5001 hypothetical protein. | HslV component of HslUV peptidase. Threonine peptidase. MEROPS family T01B; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.618 |
| Meso_3491 | Meso_3489 | Meso_3491 | Meso_3489 | PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc02576 hypothetical acetyltransferase protein. | KEGG: mlo:mll5001 hypothetical protein. | 0.649 |
| Meso_3491 | Meso_3494 | Meso_3491 | Meso_3494 | PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc02576 hypothetical acetyltransferase protein. | KEGG: mlo:mlr5010 hypothetical protein. | 0.585 |
| Meso_3491 | coaA | Meso_3491 | Meso_3499 | PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc02576 hypothetical acetyltransferase protein. | TIGRFAM: pantothenate kinase; PFAM: phosphoribulokinase/uridine kinase; KEGG: mlo:mlr5019 pantothenate kinase. | 0.583 |
| Meso_3491 | hisA | Meso_3491 | Meso_3496 | PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc02576 hypothetical acetyltransferase protein. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis; KEGG: sme:SMc02570 probable phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase protein. | 0.586 |
| Meso_3491 | hisB | Meso_3491 | Meso_3493 | PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc02576 hypothetical acetyltransferase protein. | PFAM: imidazoleglycerol-phosphate dehydratase; KEGG: mlo:mlr5008 imidazoleglycerol-phosphate dehydratase. | 0.610 |
| Meso_3491 | hisE | Meso_3491 | Meso_3498 | PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc02576 hypothetical acetyltransferase protein. | PFAM: phosphoribosyl-ATP pyrophosphohydrolase; KEGG: mlo:mlr5018 phosphoribosyl-ATP pyrophosphatase. | 0.583 |
| Meso_3491 | hisF | Meso_3491 | Meso_3497 | PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc02576 hypothetical acetyltransferase protein. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.586 |
| Meso_3491 | hisH | Meso_3491 | Meso_3495 | PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc02576 hypothetical acetyltransferase protein. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.598 |
| Meso_3491 | hslU | Meso_3491 | Meso_3490 | PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc02576 hypothetical acetyltransferase protein. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.846 |
| Meso_3491 | hslV | Meso_3491 | Meso_3492 | PFAM: GCN5-related N-acetyltransferase; KEGG: sme:SMc02576 hypothetical acetyltransferase protein. | HslV component of HslUV peptidase. Threonine peptidase. MEROPS family T01B; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.838 |
