| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_1648 | Meso_3677 | Meso_1648 | Meso_3677 | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | PFAM: tRNA/rRNA methyltransferase (SpoU) RNA 2-O ribose methyltransferase, substrate binding; KEGG: mlo:mlr3210 rRNA methylase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.693 |
| Meso_1648 | rplC | Meso_1648 | Meso_1678 | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.831 |
| Meso_1648 | rplM | Meso_1648 | Meso_1164 | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.783 |
| Meso_1648 | rplO | Meso_1648 | Meso_1659 | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.784 |
| Meso_1648 | rplQ | Meso_1648 | Meso_1653 | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | PFAM: ribosomal protein L17; KEGG: ret:RHE_CH01700 50S ribosomal protein L17. | 0.778 |
| Meso_1648 | rplU | Meso_1648 | Meso_3461 | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.766 |
| Meso_1648 | rplX | Meso_1648 | Meso_1667 | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.792 |
| Meso_1648 | rsfS | Meso_1648 | Meso_3454 | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.740 |
| Meso_3676 | Meso_3677 | Meso_3676 | Meso_3677 | PFAM: conserved hypothetical protein 95; KEGG: mlo:mlr3209 SAM dependent methyltransferase; Belongs to the methyltransferase superfamily. | PFAM: tRNA/rRNA methyltransferase (SpoU) RNA 2-O ribose methyltransferase, substrate binding; KEGG: mlo:mlr3210 rRNA methylase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.957 |
| Meso_3676 | lspA | Meso_3676 | Meso_3678 | PFAM: conserved hypothetical protein 95; KEGG: mlo:mlr3209 SAM dependent methyltransferase; Belongs to the methyltransferase superfamily. | Signal peptidase II. Aspartic peptidase. MEROPS family A08; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.836 |
| Meso_3677 | Meso_1648 | Meso_3677 | Meso_1648 | PFAM: tRNA/rRNA methyltransferase (SpoU) RNA 2-O ribose methyltransferase, substrate binding; KEGG: mlo:mlr3210 rRNA methylase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.693 |
| Meso_3677 | Meso_3676 | Meso_3677 | Meso_3676 | PFAM: tRNA/rRNA methyltransferase (SpoU) RNA 2-O ribose methyltransferase, substrate binding; KEGG: mlo:mlr3210 rRNA methylase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | PFAM: conserved hypothetical protein 95; KEGG: mlo:mlr3209 SAM dependent methyltransferase; Belongs to the methyltransferase superfamily. | 0.957 |
| Meso_3677 | lspA | Meso_3677 | Meso_3678 | PFAM: tRNA/rRNA methyltransferase (SpoU) RNA 2-O ribose methyltransferase, substrate binding; KEGG: mlo:mlr3210 rRNA methylase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Signal peptidase II. Aspartic peptidase. MEROPS family A08; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.837 |
| Meso_3677 | rplC | Meso_3677 | Meso_1678 | PFAM: tRNA/rRNA methyltransferase (SpoU) RNA 2-O ribose methyltransferase, substrate binding; KEGG: mlo:mlr3210 rRNA methylase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.713 |
| Meso_3677 | rplM | Meso_3677 | Meso_1164 | PFAM: tRNA/rRNA methyltransferase (SpoU) RNA 2-O ribose methyltransferase, substrate binding; KEGG: mlo:mlr3210 rRNA methylase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.740 |
| Meso_3677 | rplO | Meso_3677 | Meso_1659 | PFAM: tRNA/rRNA methyltransferase (SpoU) RNA 2-O ribose methyltransferase, substrate binding; KEGG: mlo:mlr3210 rRNA methylase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.734 |
| Meso_3677 | rplQ | Meso_3677 | Meso_1653 | PFAM: tRNA/rRNA methyltransferase (SpoU) RNA 2-O ribose methyltransferase, substrate binding; KEGG: mlo:mlr3210 rRNA methylase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | PFAM: ribosomal protein L17; KEGG: ret:RHE_CH01700 50S ribosomal protein L17. | 0.695 |
| Meso_3677 | rplU | Meso_3677 | Meso_3461 | PFAM: tRNA/rRNA methyltransferase (SpoU) RNA 2-O ribose methyltransferase, substrate binding; KEGG: mlo:mlr3210 rRNA methylase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.702 |
| Meso_3677 | rplX | Meso_3677 | Meso_1667 | PFAM: tRNA/rRNA methyltransferase (SpoU) RNA 2-O ribose methyltransferase, substrate binding; KEGG: mlo:mlr3210 rRNA methylase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.717 |
| Meso_3677 | rsfS | Meso_3677 | Meso_3454 | PFAM: tRNA/rRNA methyltransferase (SpoU) RNA 2-O ribose methyltransferase, substrate binding; KEGG: mlo:mlr3210 rRNA methylase; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.724 |
