| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_0002 | Meso_0541 | Meso_0002 | Meso_0541 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: SNF2-related helicase-like type III restriction enzyme, res subunit; SMART: DEAD/DEAH box helicase-like; KEGG: ecc:c5378 hypothetical protein. | 0.886 |
| Meso_0002 | Meso_1150 | Meso_0002 | Meso_1150 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA ligase LigD polymerase module; PFAM: ATP dependent DNA ligase-like ATP dependent DNA ligase; KEGG: atc:AGR_L_502 probable ATP-dependent DNA ligase PA2138. | 0.852 |
| Meso_0002 | Meso_1199 | Meso_0002 | Meso_1199 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: helicase-like; SMART: DEAD/DEAH box helicase-like; KEGG: sas:SAS0928 hypothetical protein. | 0.625 |
| Meso_0002 | Meso_1582 | Meso_0002 | Meso_1582 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: mlo:mll0423 DNA polymerase III, delta prime subunit. | 0.998 |
| Meso_0002 | Meso_2703 | Meso_0002 | Meso_2703 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.801 |
| Meso_0002 | mutL | Meso_0002 | Meso_0441 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.937 |
| Meso_0002 | mutS | Meso_0002 | Meso_4031 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.941 |
| Meso_0002 | polA | Meso_0002 | Meso_3945 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.982 |
| Meso_0002 | recA | Meso_0002 | Meso_1263 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.914 |
| Meso_0002 | rnhB | Meso_0002 | Meso_0703 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.906 |
| Meso_0541 | Meso_0002 | Meso_0541 | Meso_0002 | PFAM: SNF2-related helicase-like type III restriction enzyme, res subunit; SMART: DEAD/DEAH box helicase-like; KEGG: ecc:c5378 hypothetical protein. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.886 |
| Meso_0541 | Meso_1150 | Meso_0541 | Meso_1150 | PFAM: SNF2-related helicase-like type III restriction enzyme, res subunit; SMART: DEAD/DEAH box helicase-like; KEGG: ecc:c5378 hypothetical protein. | ATP-dependent DNA ligase LigD polymerase module; PFAM: ATP dependent DNA ligase-like ATP dependent DNA ligase; KEGG: atc:AGR_L_502 probable ATP-dependent DNA ligase PA2138. | 0.668 |
| Meso_0541 | Meso_1199 | Meso_0541 | Meso_1199 | PFAM: SNF2-related helicase-like type III restriction enzyme, res subunit; SMART: DEAD/DEAH box helicase-like; KEGG: ecc:c5378 hypothetical protein. | PFAM: helicase-like; SMART: DEAD/DEAH box helicase-like; KEGG: sas:SAS0928 hypothetical protein. | 0.667 |
| Meso_0541 | Meso_1582 | Meso_0541 | Meso_1582 | PFAM: SNF2-related helicase-like type III restriction enzyme, res subunit; SMART: DEAD/DEAH box helicase-like; KEGG: ecc:c5378 hypothetical protein. | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: mlo:mll0423 DNA polymerase III, delta prime subunit. | 0.526 |
| Meso_0541 | polA | Meso_0541 | Meso_3945 | PFAM: SNF2-related helicase-like type III restriction enzyme, res subunit; SMART: DEAD/DEAH box helicase-like; KEGG: ecc:c5378 hypothetical protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.942 |
| Meso_0541 | recA | Meso_0541 | Meso_1263 | PFAM: SNF2-related helicase-like type III restriction enzyme, res subunit; SMART: DEAD/DEAH box helicase-like; KEGG: ecc:c5378 hypothetical protein. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.825 |
| Meso_1150 | Meso_0002 | Meso_1150 | Meso_0002 | ATP-dependent DNA ligase LigD polymerase module; PFAM: ATP dependent DNA ligase-like ATP dependent DNA ligase; KEGG: atc:AGR_L_502 probable ATP-dependent DNA ligase PA2138. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.852 |
| Meso_1150 | Meso_0541 | Meso_1150 | Meso_0541 | ATP-dependent DNA ligase LigD polymerase module; PFAM: ATP dependent DNA ligase-like ATP dependent DNA ligase; KEGG: atc:AGR_L_502 probable ATP-dependent DNA ligase PA2138. | PFAM: SNF2-related helicase-like type III restriction enzyme, res subunit; SMART: DEAD/DEAH box helicase-like; KEGG: ecc:c5378 hypothetical protein. | 0.668 |
| Meso_1150 | Meso_1582 | Meso_1150 | Meso_1582 | ATP-dependent DNA ligase LigD polymerase module; PFAM: ATP dependent DNA ligase-like ATP dependent DNA ligase; KEGG: atc:AGR_L_502 probable ATP-dependent DNA ligase PA2138. | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: mlo:mll0423 DNA polymerase III, delta prime subunit. | 0.490 |
| Meso_1150 | mutS | Meso_1150 | Meso_4031 | ATP-dependent DNA ligase LigD polymerase module; PFAM: ATP dependent DNA ligase-like ATP dependent DNA ligase; KEGG: atc:AGR_L_502 probable ATP-dependent DNA ligase PA2138. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.595 |
