| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_0056 | Meso_1536 | Meso_0056 | Meso_1536 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating). | 0.967 |
| Meso_0056 | Meso_1629 | Meso_0056 | Meso_1629 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.463 |
| Meso_0056 | Meso_3256 | Meso_0056 | Meso_3256 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | PFAM: pyruvate kinase; KEGG: mlo:mll3819 pyruvate kinase; Belongs to the pyruvate kinase family. | 0.667 |
| Meso_0056 | Meso_3329 | Meso_0056 | Meso_3329 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.530 |
| Meso_0056 | Meso_3621 | Meso_0056 | Meso_3621 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | PFAM: fumarate lyase; KEGG: cme:CMD058C fumarate hydratase precursor. | 0.966 |
| Meso_0056 | Meso_4030 | Meso_0056 | Meso_4030 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr5329 NADP-dependent malic enzyme. | 0.966 |
| Meso_0056 | fumC | Meso_0056 | Meso_0355 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.966 |
| Meso_0056 | glcB | Meso_0056 | Meso_3915 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.946 |
| Meso_0056 | mdh | Meso_0056 | Meso_3395 | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.992 |
| Meso_1536 | Meso_0056 | Meso_1536 | Meso_0056 | Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating). | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.967 |
| Meso_1536 | Meso_1629 | Meso_1536 | Meso_1629 | Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating). | Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.977 |
| Meso_1536 | Meso_3256 | Meso_1536 | Meso_3256 | Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating). | PFAM: pyruvate kinase; KEGG: mlo:mll3819 pyruvate kinase; Belongs to the pyruvate kinase family. | 0.966 |
| Meso_1536 | Meso_3329 | Meso_1536 | Meso_3329 | Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating). | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.955 |
| Meso_1536 | Meso_3621 | Meso_1536 | Meso_3621 | Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating). | PFAM: fumarate lyase; KEGG: cme:CMD058C fumarate hydratase precursor. | 0.961 |
| Meso_1536 | Meso_4030 | Meso_1536 | Meso_4030 | Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating). | PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr5329 NADP-dependent malic enzyme. | 0.952 |
| Meso_1536 | fumC | Meso_1536 | Meso_0355 | Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating). | Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.961 |
| Meso_1536 | glcB | Meso_1536 | Meso_3915 | Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating). | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.981 |
| Meso_1536 | mdh | Meso_1536 | Meso_3395 | Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating). | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.974 |
| Meso_1536 | pdhA | Meso_1536 | Meso_1630 | Malic enzyme, NAD-binding protein; PFAM: phosphate acetyl/butaryl transferase malic enzyme-like malic enzyme, NAD-binding; KEGG: mlo:mlr0809 malate dehydrogenase (decarboxylating). | Dehydrogenase, E1 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.958 |
| Meso_1629 | Meso_0056 | Meso_1629 | Meso_0056 | Transketolase, central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.463 |
