| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Meso_2199 | guaA | Meso_2199 | Meso_0495 | TIGRFAM: glutamine amidotransferase of anthranilate synthase anthranilate synthase; PFAM: glutamine amidotransferase class-I Anthranilate synthase component I and chorismate binding protein Anthranilate synthase component I-like; KEGG: mlo:mlr2774 anthranilate synthase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.489 |
| Meso_2199 | polA | Meso_2199 | Meso_3945 | TIGRFAM: glutamine amidotransferase of anthranilate synthase anthranilate synthase; PFAM: glutamine amidotransferase class-I Anthranilate synthase component I and chorismate binding protein Anthranilate synthase component I-like; KEGG: mlo:mlr2774 anthranilate synthase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.577 |
| Meso_2199 | trpS | Meso_2199 | Meso_4035 | TIGRFAM: glutamine amidotransferase of anthranilate synthase anthranilate synthase; PFAM: glutamine amidotransferase class-I Anthranilate synthase component I and chorismate binding protein Anthranilate synthase component I-like; KEGG: mlo:mlr2774 anthranilate synthase. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.619 |
| Meso_4036 | murJ | Meso_4036 | Meso_4034 | UspA; PFAM: UspA; KEGG: mlo:mll5316 hypothetical protein. | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | 0.505 |
| Meso_4036 | trpS | Meso_4036 | Meso_4035 | UspA; PFAM: UspA; KEGG: mlo:mll5316 hypothetical protein. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.680 |
| guaA | Meso_2199 | Meso_0495 | Meso_2199 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | TIGRFAM: glutamine amidotransferase of anthranilate synthase anthranilate synthase; PFAM: glutamine amidotransferase class-I Anthranilate synthase component I and chorismate binding protein Anthranilate synthase component I-like; KEGG: mlo:mlr2774 anthranilate synthase. | 0.489 |
| guaA | lepA | Meso_0495 | Meso_4075 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.537 |
| guaA | pheT | Meso_0495 | Meso_0677 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: mlo:mll5053 phenylalanine-tRNA ligase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.864 |
| guaA | polA | Meso_0495 | Meso_3945 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.742 |
| guaA | serS | Meso_0495 | Meso_1803 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.549 |
| guaA | trpS | Meso_0495 | Meso_4035 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.600 |
| guaA | valS | Meso_0495 | Meso_1571 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.889 |
| lepA | guaA | Meso_4075 | Meso_0495 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.537 |
| lepA | pheT | Meso_4075 | Meso_0677 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: mlo:mll5053 phenylalanine-tRNA ligase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.603 |
| lepA | polA | Meso_4075 | Meso_3945 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.604 |
| lepA | serS | Meso_4075 | Meso_1803 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.526 |
| lepA | trpS | Meso_4075 | Meso_4035 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.640 |
| lepA | tyrS | Meso_4075 | Meso_1785 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. | 0.525 |
| lepA | valS | Meso_4075 | Meso_1571 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. | 0.421 |
| murJ | Meso_4036 | Meso_4034 | Meso_4036 | Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. | UspA; PFAM: UspA; KEGG: mlo:mll5316 hypothetical protein. | 0.505 |
