node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Meso_0029 | mutM | Meso_0029 | Meso_4100 | DEAD/H associated; PFAM: helicase-like DEAD/DEAH box helicase-like DEAD/H associated; KEGG: mlo:mlr5610 probable ATP dependent DNA helicase. | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.699 |
Meso_0029 | uvrC | Meso_0029 | Meso_1975 | DEAD/H associated; PFAM: helicase-like DEAD/DEAH box helicase-like DEAD/H associated; KEGG: mlo:mlr5610 probable ATP dependent DNA helicase. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.479 |
Meso_2349 | mutM | Meso_2349 | Meso_4100 | Xanthosine triphosphate pyrophosphatase-like protein; KEGG: pto:PTO0809 hypothetical protein. | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.726 |
Meso_2349 | nth | Meso_2349 | Meso_3567 | Xanthosine triphosphate pyrophosphatase-like protein; KEGG: pto:PTO0809 hypothetical protein. | Endonuclease III / DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.564 |
Meso_2349 | polA | Meso_2349 | Meso_3945 | Xanthosine triphosphate pyrophosphatase-like protein; KEGG: pto:PTO0809 hypothetical protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.674 |
Meso_4097 | Meso_4098 | Meso_4097 | Meso_4098 | PFAM: TadE-like; KEGG: bja:blr3942 hypothetical protein. | KEGG: mlo:mll5590 hypothetical protein. | 0.938 |
Meso_4097 | Meso_4101 | Meso_4097 | Meso_4101 | PFAM: TadE-like; KEGG: bja:blr3942 hypothetical protein. | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mlo:mll5584 enoyl CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.481 |
Meso_4097 | deoB | Meso_4097 | Meso_4099 | PFAM: TadE-like; KEGG: bja:blr3942 hypothetical protein. | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | 0.585 |
Meso_4097 | mutM | Meso_4097 | Meso_4100 | PFAM: TadE-like; KEGG: bja:blr3942 hypothetical protein. | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.581 |
Meso_4098 | Meso_4097 | Meso_4098 | Meso_4097 | KEGG: mlo:mll5590 hypothetical protein. | PFAM: TadE-like; KEGG: bja:blr3942 hypothetical protein. | 0.938 |
Meso_4098 | Meso_4101 | Meso_4098 | Meso_4101 | KEGG: mlo:mll5590 hypothetical protein. | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mlo:mll5584 enoyl CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.522 |
Meso_4098 | deoB | Meso_4098 | Meso_4099 | KEGG: mlo:mll5590 hypothetical protein. | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | 0.628 |
Meso_4098 | mutM | Meso_4098 | Meso_4100 | KEGG: mlo:mll5590 hypothetical protein. | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.628 |
Meso_4101 | Meso_4097 | Meso_4101 | Meso_4097 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mlo:mll5584 enoyl CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | PFAM: TadE-like; KEGG: bja:blr3942 hypothetical protein. | 0.481 |
Meso_4101 | Meso_4098 | Meso_4101 | Meso_4098 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mlo:mll5584 enoyl CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | KEGG: mlo:mll5590 hypothetical protein. | 0.522 |
Meso_4101 | deoB | Meso_4101 | Meso_4099 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mlo:mll5584 enoyl CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | 0.691 |
Meso_4101 | mutM | Meso_4101 | Meso_4100 | PFAM: Enoyl-CoA hydratase/isomerase; KEGG: mlo:mll5584 enoyl CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.690 |
coaE | mutM | Meso_3481 | Meso_4100 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.875 |
coaE | nth | Meso_3481 | Meso_3567 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Endonuclease III / DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.411 |
coaE | polA | Meso_3481 | Meso_3945 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.629 |